Evidence map›Paper›PMID 32496191›Full record

ArticleeLife2020

Genome editing enables reverse genetics of multicellular development in the choanoflagellate

David S Booth, Nicole King

Abstract readEvaluation Study
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Evolutionary cell biology comes of age.Journal of cell science · 2025
    Article
  2. Review
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  4. Article
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  9. Cell differentiation controls iron assimilation in a choanoflagellate.bioRxiv : the preprint server for biology · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David S BoothHoward Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0002-4724-4702
Nicole KingHoward Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0002-6409-1111

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

In a previous study, we established a forward genetic screen to identify genes required for multicellular development in the choanoflagellate,

Indexed as

ChoanoflagellataCRISPR-Cas SystemsGene EditingGenome, ProtozoanLectins, C-TypeProtozoan ProteinsReverse GeneticsLectins, C-TypeProtozoan Proteinschoanoflagellatesdevelopmental biologygeneticsgenome editinggenomicsmulticellularitySalpingoeca rosetta

Identifiers

PMID32496191
PMCPMC7314544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.