Evidence map›Paper›PMID 32495404›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2021

Iron Oxide Nanoparticles as T

Mike Jeon, Mackenzie V Halbert, Zachary R Stephen, Miqin Zhang

Registry-linked trialAbstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06551805 (Clinical Research Protocol of Ferumoxytol for Magnetic Resonance Enhancement Imaging in Patients With Atherosclerosis.), which is not on this map. Cited by 146 papers.

0numbers the graph read from it
0cells of the map it votes in
146citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06551805 recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Research Protocol of Ferumoxytol for Magnetic Resonance Enhancement Imaging in Patients With Atherosclerosis.

TypeobservationalSponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolRan2024 to 2026Enrolled100ConditionsAtherosclerosisArmsSafety assessment of Ferumoxytol., Assessment of the diagnostic value of Ferumoxytol for MR angiography.
3 · Its place in the literature

Who cites it

146 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Nanomaterials-Based Immunotherapy for Atherosclerosis.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Contrast Agents for Enhanced Bioimaging: A Comprehensive Review.Chembiochem : a European journal of chemical biology · 2026
    Review
  10. Slowing Down Water: Enhanced and Cation-responsive MRI Contrast.Angewandte Chemie (International ed. in English) · 2026
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Magnetic nanoparticles as promising materials for the future of medicine.Journal of materials science. Materials in medicine · 2026
    Review
  20. Carbon Dots Meet MRI: Metal Doping for a Smart Contrast Agent Design.International journal of molecular sciences · 2026
    Review

86 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mike JeonDepartment of Materials Science & Engineering, University of Washington, Seattle, WA, 98195, USA.
Mackenzie V HalbertDepartment of Materials Science & Engineering, University of Washington, Seattle, WA, 98195, USA.
Zachary R StephenDepartment of Materials Science & Engineering, University of Washington, Seattle, WA, 98195, USA.
Miqin ZhangDepartment of Materials Science & Engineering, University of Washington, Seattle, WA, 98195, USA.ORCID https://orcid.org/0000-0001-8974-1494

Funding

Iron oxide nanotheranostics for breast cancerR01EB026890 · NIBIB · UNIVERSITY OF WASHINGTON · PI ZHANG, MIQIN · 2018 to 2021
$1.9M
Kyocera Professor EndowmentNIBIB NIH HHS R01 EB026890NIH HHS R01EB026890
6 · The paper itself

Abstract

Gadolinium-based chelates are a mainstay of contrast agents for magnetic resonance imaging (MRI) in the clinic. However, their toxicity elicits severe side effects and the Food and Drug Administration has issued many warnings about their potential retention in patients' bodies, which causes safety concerns. Iron oxide nanoparticles (IONPs) are a potentially attractive alternative, because of their nontoxic and biodegradable nature. Studies in developing IONPs as T

Indexed as

Contrast MediaMagnetic Resonance ImagingAnimalsGadoliniumHumansMagnetic Iron Oxide NanoparticlesContrast MediaGadoliniumgadoliniumiron oxide nanoparticlesmagnetic resonance imagingMRI contrast agentsnanoparticlesT 1 contrast agents

Identifiers

PMID32495404
PMCPMC8022883

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.