Evidence map›Paper›PMID 32495258›Full record

ArticleForensic science, medicine, and pathology2020

Sudden death of a young adult with coronary artery vasculitis, coronary aneurysms, parvovirus B19 infection and Kawasaki disease.

Stefan Flossdorf, Karl Heinz Schiwy-Bochat, Daniela Teifel, Jochen W U Fries, Markus A Rothschild

Abstract readCase Reports
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In one paragraph

Article in Forensic science, medicine, and pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Stefan FlossdorfMedical Faculty, Institute of Legal Medicine, University of Cologne, Melatengürtel 60-62, 50823, Cologne, Germany. stefan.flossdorf@uk-koeln.de.ORCID 0000-0001-5557-9935
Karl Heinz Schiwy-BochatMedical Faculty, Institute of Legal Medicine, University of Cologne, Melatengürtel 60-62, 50823, Cologne, Germany.
Daniela TeifelMedical Faculty, Institute of Legal Medicine, University of Cologne, Melatengürtel 60-62, 50823, Cologne, Germany.
Jochen W U FriesMedical Faculty, Institute of Pathology, University Hospital of Cologne, Kerpener Str. 63, 50937, Cologne, Germany.
Markus A RothschildMedical Faculty, Institute of Legal Medicine, University of Cologne, Melatengürtel 60-62, 50823, Cologne, Germany.
University of Cologne · DETH Köln - University of Applied Sciences · DEUniversity Hospital Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of a 20-year-old man who suffered from Kawasaki disease (KD) associated with a florid parvovirus infection, and who died suddenly from thrombotic occlusion of the coronary arteries. The autopsy revealed several aneurysms of the coronary arteries, a chronic vasculitis and a myofibroblast proliferation leading to focal luminal narrowing. The inflammatory response as well as the detection of the viral particles by PCR in blood and in the lesional tissue demonstrated a possible cause by Parvovirus infection. The expression of endoglin on endothelial cells of neoangiogenesis indicates the involvement of the TGF-beta pathway, necessary for maintaining chronic inflammation. In addition, a possible connection between the intake of methylphenidate, arteritis and a possible pre-existing heart disease must be discussed. Furthermore, KD must also be considered as a cause of sudden death in the adult population.

Indexed as

ArteritisCoronary AneurysmCoronary ThrombosisCoronary VesselsDeath, SuddenErythema InfectiosumHumansMaleMucocutaneous Lymph Node SyndromeMyocardial InfarctionYoung AdultAdultCoronary artery aneurysmEndoglinKawasaki diseaseMethylphenidatParvovirus

Identifiers

PMID32495258
OpenAlexW3028624197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.