Evidence map›Paper›PMID 32495072›Full record

ArticleObesity surgery2020

Weight Loss After Bariatric Surgery Significantly Improves Carotid and Cardiac Function in Apparently Healthy People with Morbid Obesity.

Alessandro Giudici, Carlo Palombo, Michaela Kozakova, Carmela Morizzo, Lorenzo Losso, Monica Nannipieri, Rossana Berta, Alun D Hughes, J Kennedy Cruickshank, Ashraf W Khir

Open access · hybridAbstract read
In one paragraph

Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Alessandro GiudiciDepartment of Mechanical and Aerospace Engineering, Brunel University London, Kingston Lane, Uxbridge, Middlesex, UB8 3PH, UK.
Carlo PalomboDepartment of Surgical, Medical, Molecular Pathology and Critical Area Medicine, University of Pisa, Pisa, Tuscany, Italy.
Michaela KozakovaDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Tuscany, Italy.
Carmela MorizzoDepartment of Surgical, Medical, Molecular Pathology and Critical Area Medicine, University of Pisa, Pisa, Tuscany, Italy.
Lorenzo LossoDepartment of Surgical, Medical, Molecular Pathology and Critical Area Medicine, University of Pisa, Pisa, Tuscany, Italy.
Monica NannipieriDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Tuscany, Italy.
Rossana BertaBariatric Surgery Division, Azienda Ospedaliero Universitaria Pisana, Pisa, Tuscany, Italy.
Alun D HughesDepartment of Population Science & Experimental Medicine, Institute of Cardiovascular Science, University College London, London, Middlesex, UK.
J Kennedy CruickshankSchool of Life-Course/Nutritional Sciences, King's College, St. Thomas' & Guy's Hospitals, London, Middlesex, UK.
Ashraf W KhirDepartment of Mechanical and Aerospace Engineering, Brunel University London, Kingston Lane, Uxbridge, Middlesex, UB8 3PH, UK. ashraf.khir@brunel.ac.uk.ORCID 0000-0002-0845-2891
University of Pisa · ITBrunel University of London · GBAzienda Ospedaliera Universitaria Pisana · ITGuy's Hospital · GBUniversity College London · GB

Funding

British Heart Foundation CS/13/1/30327British Heart Foundation CS/15/6/31468British Heart Foundation IG/18/5/33958British Heart Foundation PG/13/6/29934British Heart Foundation PG/15/75/31748British Heart Foundation PG/17/90/33415Medical Research Council MR/P023444/1UK Medical Research Council MC_UU_12019/1
6 · The paper itself

Abstract

purposeObesity clearly increases cardiovascular risk, often inducing high blood pressure (BP), impaired left ventricular (LV) function, and increased arterial stiffness. Intensive weight loss and bariatric surgery induce improvement in hypertension and diabetes for morbid obesity. Carotid artery haemodynamics is a powerful prognostic indicator for stroke and cognitive decline independent of BP. The aim of this study was to evaluate the impact of a 3-stage bariatric strategy of diet, bariatric surgery, and consequent weight loss on carotid haemodynamics and cardiac diastolic function. MATERIAL AND

methodsThis prospective study included 26 patients (45 ± 10 years, 4 men) with severe obesity undergoing bariatric surgery without comorbidities (hypertension, diabetes, etc.). Anthropometry, BP, Doppler echocardiography, and common carotid haemodynamics by ultrasound were measured at three times: (1) baseline, (2) after 1-month diet (post-diet), and (3) 8 months after surgery (post-surgery). The lnDU-loop method was used to estimate local carotid pulse wave velocity (

resultsBaseline BMI was 47.9 ± 7.1 kg/m

conclusionWeight loss following diet and bariatric surgery is associated with reduced carotid arterial stiffness and improved LV diastolic function. Diet and bariatric surgery are effective treatments for morbid obesity with its concomitant adverse cardiovascular effects.

Indexed as

Bariatric SurgeryObesity, MorbidCarotid ArteriesFemaleHumansMaleProspective StudiesPulse Wave AnalysisWeight LossBariatric surgeryCarotid arteryCarotid local PWVlnDU-loopLV functionObesity

Identifiers

PMID32495072
PMCPMC7651614
OpenAlexW3025113653

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.