Evidence map›Paper›PMID 32495050›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2021

Implementing preoperative Botulinum toxin A and progressive pneumoperitoneum through the use of an algorithm in giant ventral hernia repair.

Y Yurtkap, M M J van Rooijen, S Roels, J M L Bosmans, O Uyttebroek, J F Lange, F Berrevoet

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PubMed Publisher
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 5 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Botulinum toxin A in complex incisional hernia repair: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Pooled it
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  6. Article
  7. Article
  8. Complex Abdominal Wall Hernias: Structured Use of Adjuvant Therapies.Journal of abdominal wall surgery : JAWS · 2025
    Article
  9. Observational
  10. Intra-abdominal hypertension and compartment syndrome after complex hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Y Yurtkap *Department of Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands.
M M J van Rooijen *Department of Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands.
S RoelsDepartment of Radiology, Ghent University Hospital, Ghent, Belgium.
J M L BosmansDepartment of Radiology, Ghent University Hospital, Ghent, Belgium.
O UyttebroekDepartment of General and HPB Surgery and Liver Transplantation, Ghent University Hospital, Ghent, Belgium.
J F LangeDepartment of Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands.
F BerrevoetDepartment of General and HPB Surgery and Liver Transplantation, Ghent University Hospital, Ghent, Belgium. Frederik.Berrevoet@UGent.be.ORCID 0000-0002-3575-5345
Ghent University Hospital · BEErasmus University Rotterdam · NLIJsselland Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRepair of large ventral hernias with loss of domain can be facilitated by preoperative Botulinum toxin A (BTA) injections and preoperative progressive pneumoperitoneum (PPP). The aim of this study is to evaluate the outcomes of ventral hernioplasty using a standardized algorithm, including component separation techniques, preoperative BTA and PPP.

methodsAll patients between June 2014 and August 2018 with giant hernias (either primary or incisional) of more than 12 cm width were treated according to a previously developed standardized algorithm. Retrospective data analysis from a prospectively collected dataset was performed. The primary outcome was closure of the anterior fascia. Secondary outcomes included complications related to the preoperative treatment, postoperative complications, and recurrences.

resultsTwenty-three patients were included. Median age was 65 years (range 28-77) and median BMI was 31.4 (range 22.7-38.0 kg/m

conclusionOur algorithm using both anterior or posterior component separation, together with preoperative BTA injections and PPP, achieved an acceptable fascial closure rate. Further studies are needed to explore the individual potential of BTA injections and PPP, and to research whether these methods can prevent the need for component separation, as postoperative wound morbidity remains high in our study.

Indexed as

Botulinum Toxins, Type AHernia, VentralPneumoperitoneumAbdominal MusclesAdultAgedAlgorithmsHerniorrhaphyHumansMiddle AgedPreoperative CareRecurrenceRetrospective StudiesSurgical MeshBotulinum Toxins, Type ABotulinum AComponent separation techniquesLoss of domainProgressive pneumoperitoneumVentral hernia

Identifiers

PMID32495050
OpenAlexW3028749197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.