Evidence map›Paper›PMID 32495023›Full record

SynthesisInternational urology and nephrology2020

Prognostic value of left ventricular global longitudinal strain in chronic kidney disease patients: a systematic review and meta-analysis.

Tao Zhang, Jing Li, Shili Cao

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International urology and nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Imaging of Congestion in Cardio-renal Syndrome.Current heart failure reports · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tao ZhangDepartment of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300112, People's Republic of China.
Jing LiDepartment of Nephrology, First Central Hospital of Tianjin, Tianjin, 300192, People's Republic of China. jadee_66@126.com.
Shili CaoDepartment of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300112, People's Republic of China. caoZT1949@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this meta-analysis was to evaluate whether left ventricular global longitudinal strain (GLS) is a potential marker of predicting adverse outcomes in CKD patients.

backgroundCKD is a growing health burden currently affecting 10-15% of adults worldwide, and disproportionally increasing propensity to develop cardiovascular diseases and events. Although obtained from several relatively small studies, the evidence supporting the prognostic value of GLS in patients with CKD is still building.

methodsWe conducted a Medline literature research using electronic databases (PubMed, Ovid, Embase and Web of Science) to identify relevant studies reporting the association between GLS and the primary outcomes, including all-cause mortality, major cardiac events (MCE), and cardiovascular mortality in CKD patients. Sensitivity analysis and subgroup analysis were performed to find the origin of heterogeneity.

resultsA total of 11 observational studies with 2167 patients with CKD were enrolled. In patients with CKD, GLS was associated with all-cause mortality (HR: 1.09, 95% CI 1.06-1.12) with no heterogeneity among the studies (I

conclusionsOur meta-analysis demonstrates that GLS is associated with all-cause mortality, MCE, cardiovascular mortality, and combined adverse events in CKD patients.

Indexed as

Ventricular Function, LeftHumansPrognosisRenal Insufficiency, ChronicAdverse outcomesAll-cause mortalityChronic kidney diseaseLeft ventricular ejection fractionLeft ventricular global longitudinal strain

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.