ArticleArchives of gynecology and obstetrics2020
The ovulation trigger-OPU time interval of different ovarian protocols in ART: a retrospective study.
Article in Archives of gynecology and obstetrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Time interval between hCG administration and oocyte retrieval and ART outcomes: an updated systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2023Pooled it
- Nonlinear effects of post-denudation timing on day 3 embryo outcomes in ICSI and evidence for a translatable optimization window.Journal of translational medicine · 2026Article
- Risk factors and treatment strategies for live birth in women with high BMI undergoing ART.BMC medicine · 2026Article
- Effects of hCG-to-oocyte retrieval interval on oocyte performances in women with polycystic ovary syndrome undergoing progestin-primed ovarian stimulation: a retrospective cohort trial.Journal of assisted reproduction and genetics · 2026Article
- Development of a risk model for low oocyte retrieval in first-cycle IVF patients with diminished ovarian reserve: a retrospective single-center study.Reproduction & fertility · 2026Article
- A valuable predictive model for optimizing the timing of oocyte retrieval: a retrospective analysis of oocyte retrieval time in 49,961 oocyte pickup (OPU) cycles.Reproductive biology and endocrinology : RB&E · 2025Article
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- Article
- The Effect of Trigger-to-Retrieval Time Interval on Assisted Reproductive Technology Outcomes in Patients with Poor Ovarian Response : The Effect of Trigger-to-Retrieval Time Interval on Assisted Reproductive Technology Outcomes.Galen medical journal · 2025Article
- Is there a preferred time interval between gonadotropin-releasing hormone (GnRH) agonist trigger and oocyte retrieval in GnRH antagonist cycles? A retrospective cohort of planned fertility preservation cycles.Journal of assisted reproduction and genetics · 2024Article
- Cumulus expansion is impaired with advanced reproductive age due to loss of matrix integrity and reduced hyaluronan.Aging cell · 2023Article
- Personalization of IVF-ICSI workflow based on patient characteristics improves IVF laboratory outcomes and embryo ploidy by PGT-A.Journal of ovarian research · 2022Article
- Preventing Growth Stagnation and Premature LH Surge Are the Keys to Obtaining a Viable Embryo in Monofollicular IVF Cycles: A Retrospective Cohort Study.Journal of clinical medicine · 2022Article
- Cumulative live birth rates for low-prognosis women over 5 years or 9 frozen-thawed embryo transfer cycles.BMC pregnancy and childbirth · 2022Article
- The optimal period for oocyte retrieval after the administration of recombinant human chorionic gonadotropin in in vitro fertilization.BMC pregnancy and childbirth · 2022Article
- Revisiting the Trigger-to-Oocyte Retrieval Interval: A Machine Learning-Guided Strategy for Improving Oocyte Yield in Diminished Ovarian Reserve.Reproductive medicine and biologyArticle
- The quality of human eggs and its pre-IVF incubation.Reproductive medicine and biologyReview
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10 authors.
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Abstract
purposeTo explore the trends of oocyte and pregnancy outcomes over the ovulation trigger-OPU (oocyte pickup) time interval in four mainly used COH protocols.
methodsThis retrospective study was conducted between January 2013 and July 2018. The IVF/ICSI cycles of the patients with normal ovarian reserve were included. The number of total patients was 4673, which consisted of long agonist protocol (n = 819), short agonist protocol (n = 1703), mild stimulation protocol (n = 1627), and GnRH antagonist protocol (n = 524). The primary outcome was mature oocyte rate.
resultsThe ovulation trigger-OPU time interval and COH protocol were related to cycles with > 80% MII oocytes. Four protocols showed apparently different trends of retrieved oocyte rate and mature oocyte rate over the ovulation trigger-OPU time interval, and the long agonist protocol had the most delayed time interval than other three COH protocols in retrieving more than 60% oocytes (35.4-39.6 h vs. 34.6-38.6 h vs. 32.5-37.5 h vs. 33.8-37.7 h) and getting more than 80% mature oocytes (35.0-39.7 h vs. 36.0-37.7 h vs. 34.1-35.5 h vs. 34.5-36.3 h). And the adjusted odds ratio (OR) of the cumulative live birth rate (CLBR) (OR 1.360, 95% Confidence Interval (CI) 1.156-1.549, P < 0.05) significantly increased with the trigger-OPU time interval in the long agonist protocol.
conclusionsFor getting more and mature oocytes, the ovulation trigger-OPU time intervals should be gradually prolonged from the mild stimulation protocol, the GnRH antagonist protocol, and the short protocol to the long agonist protocol. And the prolonged ovulation trigger-OPU time interval in the long agonist protocol brings higher live birth rate (LBR) and CLBR.
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