Evidence map›Paper›PMID 32494889›Full record

SynthesisRheumatology international2020

The prevalence and impact of depression in primary systemic vasculitis: a systematic review and meta-analysis.

Bradley Pittam, Sonal Gupta, Ashar E Ahmed, David M Hughes, Sizheng Steven Zhao

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Rheumatology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Anxiety and depression in patients with giant cell arteritis.Rheumatology advances in practice · 2024
    Article
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bradley PittamSchool of Medicine, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0002-0543-1657
Sonal GuptaSchool of Medicine, University of Liverpool, Liverpool, UK.
Ashar E AhmedDepartment of Rheumatology, Southport & Ormskirk Hospital, Southport, UK.
David M HughesDepartment of Biostatistics, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Sizheng Steven ZhaoDepartment of Academic Rheumatology, Liverpool University Hospitals, Liverpool, L9 7AL, UK. s.zhao8@liverpool.ac.uk.ORCID http://orcid.org/0000-0002-3558-7353
University of Liverpool · GBSouthport and Ormskirk Hospital NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the prevalence of depression among patients with primary systemic vasculitides (PSV); compare prevalence according to vasculitis type and against controls; and examine the impact of depression on PSV outcomes.

methodsWe searched Medline, PubMed, Scopus and Web of Science using a predefined protocol in accordance with PRISMA guidelines. We included all studies that reported the prevalence or impact of depression in PSV. We also included polymyalgia rheumatica (PMR) given its association with giant cell arteritis (GCA). Meta-analyses of prevalence estimates were performed using random-effects models and reported as percentages (95% confidence interval).

resultsWe reviewed a total of 15 studies that described the prevalence of depression, categorised into small (n = 10) and large vessel vasculitis (n = 7). Pooled prevalence estimate for depression in a small vessel (predominantly ANCA-associated) vasculitis was 28% (95% CI 20-38%) with significant heterogeneity (I

conclusionDepression is highly prevalent among patients with primary systemic vasculitis and associated with poorer outcomes across a range of measures in studies of small vessel disease. Further studies are needed for depression in medium and large vessel vasculitides.

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisCase-Control StudiesDepressionGiant Cell ArteritisHumansPolymyalgia RheumaticaQuality of LifeANCA associated vasculitisDepressionFatigueGiant cell arteritisPrimary systemic vasculitis

Identifiers

PMID32494889
PMCPMC7316669
OpenAlexW3029241026

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.