ArticleEuropean biophysics journal : EBJ2020
Kinetics of irreversible pore formation under constant electrical tension in giant unilamellar vesicles.
Article in European biophysics journal : EBJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Electric field-induced rupture kinetics of giant unilamellar vesicles with varying gramicidin A content in membrane.PloS one · 2026Article
- Electroporation in lipid vesicles by varying PEG-grafted lipids in their membranes: an experimental and simulation study.RSC advances · 2025Article
- Interaction of anionic FeRSC advances · 2024Review
- Probability and kinetics of rupture and electrofusion in giant unilamellar vesicles under various frequencies of direct current pulses.PloS one · 2024Article
- Article
- Effects of sugar concentration on the electroporation, size distribution and average size of charged giant unilamellar vesicles.European biophysics journal : EBJ · 2022Article
- Article
- Effects of cholesterol on the size distribution and bending modulus of lipid vesicles.PloS one · 2022Article
- Influence of sugar concentration on the vesicle compactness, deformation and membrane poration induced by anionic nanoparticles.PloS one · 2022Article
- Recent developments in the kinetics of ruptures of giant vesicles under constant tension.RSC advances · 2021Review
- On the Coupling between Mechanical Properties and Electrostatics in Biological Membranes.Membranes · 2021Review
- Analysis of purification of charged giant vesicles in a buffer using their size distribution.The European physical journal. E, Soft matter · 2021Article
- An investigation into the critical tension of electroporation in anionic lipid vesicles.European biophysics journal : EBJ · 2021Article
- A new purification technique to obtain specific size distribution of giant lipid vesicles using dual filtration.PloS one · 2021Article
- Effects of osmotic pressure on the irreversible electroporation in giant lipid vesicles.PloS one · 2021Article
- Influence of cholesterol on electroporation in lipid membranes of giant vesicles.European biophysics journal : EBJ · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Stretching in the plasma membranes of cells and lipid membranes of vesicles plays important roles in various physiological and physicochemical phenomena. Irreversible electroporation (IRE) is a minimally invasive non-thermal tumor ablation technique where a series of short electrical energy pulses with high frequency is applied to destabilize the cell membranes. IRE also induces lateral tension due to stretching in the membranes of giant unilamellar vesicles (GUVs). Here, the kinetics of irreversible pore formation under constant electrical tension in GUVs has been investigated. The GUVs are prepared by a mixture of dioleoylphosphatidylglycerol and dioleoylphosphatidylcholine using the natural swelling method. An IRE signal of frequency 1.1 kHz is applied to the GUVs through a gold-coated electrode system. Stochastic pore formation is observed for several 'single GUVs' at a particular constant tension. The time course of the fraction of intact GUVs among all the examined GUVs is fitted with a single-exponential decay function from which the rate constant of pore formation in the vesicle, k
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