Evidence map›Paper›PMID 32494780›Full record

ArticleImage analysis for moving organ, breast, and thoracic images : third International Workshop, RAMBO 2018, fourth International Workshop, BIA 2018, and first International Workshop, TIA 2018, held in conjunction with MICCAI 2018, Granada,...2018

3D Pulmonary Artery Segmentation from CTA Scans Using Deep Learning with Realistic Data Augmentation.

Karen López-Linares Román, Isaac de La Bruere, Jorge Onieva, Lasse Andresen, Jakob Qvortrup Holsting, Farbod N Rahaghi, Iván Macía, Miguel A González Ballester, Raúl San José Estepar

Open access · greenAbstract read
In one paragraph

Article in Image analysis for moving organ, breast, and thoracic images : third International Workshop, RAMBO 2018, fourth International Workshop, BIA 2018, and first International Workshop, TIA 2018, held in conjunction with MICCAI 2018, Granada,..., 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A SR-NET 3D-TO-2D ARCHITECTURE FOR PARASEPTAL EMPHYSEMA SEGMENTATION.Proceedings. IEEE International Symposium on Biomedical Imaging · 2019
    Article
  6. Abdominal Aortic Aneurysm Segmentation Using Convolutional Neural Networks Trained with Images Generated with a Synthetic Shape Model.Machine learning and medical engineering for cardiovascular health and intravascular imaging and computer assisted stenting : first International Workshop, MLMECH 2019, and 8th Joint International Workshop, CVII-STENT 2019, held in conj... · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Karen López-Linares RománVicomtech Foundation and Biodonostia, San Sebastián, Spain.
Isaac de La BruereDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Jorge OnievaApplied Chest Imaging Laboratory, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Lasse AndresenApplied Chest Imaging Laboratory, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Jakob Qvortrup HolstingApplied Chest Imaging Laboratory, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Farbod N RahaghiDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Iván MacíaVicomtech Foundation and Biodonostia, San Sebastián, Spain.
Miguel A González BallesterBCN Medtech, Universitat Pompeu Fabra, Barcelona, Spain.
Raúl San José EsteparApplied Chest Imaging Laboratory, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Brigham and Women's Hospital · USInstitució Catalana de Recerca i Estudis Avançats · ESVicomtech · ES

Funding

The clinical impact of pulmonary vascular remodeling in smokersR01HL116473 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAN JOSE ESTEPAR, RAUL, WASHKO, GEORGE R · 2013 to 2021
$5.0M
Airway Inspector: a chest imaging biomarker software platform for COPDR01HL116931 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAN JOSE ESTEPAR, RAUL · 2013 to 2017
$2.2M
NHLBI NIH HHS R01 HL116473NHLBI NIH HHS R01 HL116931
6 · The paper itself

Abstract

The characterization of the vasculature in the mediastinum, more specifically the pulmonary artery, is of vital importance for the evaluation of several pulmonary vascular diseases. Thus, the goal of this study is to automatically segment the pulmonary artery (PA) from computed tomography angiography images, which opens up the opportunity for more complex analysis of the evolution of the PA geometry in health and disease and can be used in complex fluid mechanics models or individualized medicine. For that purpose, a new 3D convolutional neural network architecture is proposed, which is trained on images coming from different patient cohorts. The network makes use a strong data augmentation paradigm based on realistic deformations generated by applying principal component analysis to the deformation fields obtained from the affine registration of several datasets. The network is validated on 91 datasets by comparing the automatic segmentations with semi-automatically delineated ground truths in terms of mean Dice and Jaccard coefficients and mean distance between surfaces, which yields values of 0.89, 0.80 and 1.25 mm, respectively. Finally, a comparison against a Unet architecture is also included.

Indexed as

CTA Convolutional neural networkDeep learningPulmonary arterySegmentation

Identifiers

PMID32494780
PMCPMC7269186
OpenAlexW2891233083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.