Evidence map›Paper›PMID 32494765›Full record

ArticleInternational journal of reproductive biomedicine2020

Toxicity study of ethanolic stem bark extract of

Ben Enoluomen Ehigiator, Elias Adikwu

Open access · goldAbstract read
In one paragraph

Article in International journal of reproductive biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ben Enoluomen EhigiatorDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Madonna University, Nigeria.
Elias AdikwuDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Niger Delta University, Nigeria.
Madonna University · NGNiger Delta University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe uses of toxicologically unscreened plants to enhance fertility can be associated with adverse consequences.

objectiveThis study aimed to evaluate the effect of the ethanolic stem back extract of MATERIALS AND

methodsSixty male albino rats (weighing 200-250 gr) were grouped and administered by gavage with 200-800 mg/kg of EEXA daily for 15, 30, and 60 days. After the administration of EEXA, the rats were weighed and sacrificed. Blood samples were collected, serum samples were extracted, and evaluated for testosterone, follicle stimulating hormone, prolactin, estradiol, luteinizing hormone and progesterone levels. The testes, epididymis, and prostrate were harvested, weighed and testes were evaluated for sperm parameters.

resultsSignificant increase in body weight (p = 0.02) with significant decreases in testes (p = 0.01), epididymis (p = 0.01), and prostate (p = 0.02) weights occurred in rats administered with EEXA when compared to the control group. Significant (p

conclusionThe findings in this study showed that the use of

Indexed as

HormoneRat.SpermToxicityXylopia aethiopica

Identifiers

PMID32494765
PMCPMC7218670
OpenAlexW3021585909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.