ArticleScience advances2020
Avalanches and power law behavior in aortic dissection propagation.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The trial behind it
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Who cites it
25 citing papers in PubMed.
- Controlled intramural fluid injection to quantify propensity to thoracic aortic dissection.Research square · 2026Article
- Increased medial collagen enhances aortic resilience against mural delamination from hydraulic fracturing.bioRxiv : the preprint server for biology · 2026Article
- Controlled intramural fluid injection to quantify propensity to thoracic aortic dissection.bioRxiv : the preprint server for biology · 2026Article
- Erosion or Explosion: Integrated Single-Cell Transcriptomics Reveals Cellular Heterogeneity in Aortic Aneurysm and Dissection.Inflammation · 2026Article
- Neutrophil-to-albumin ratio predicts 30-day mortality in acute aortic dissection: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Patient-specific computational simulation for thoracic endovascular aortic repair in patients with Stanford type B aortic dissection.Frontiers in cardiovascular medicine · 2026Article
- Aortic dissection as a disease of vascular wall homeostasis: integrating vasa vasorum-inflammation-metabolism axis for mechanistic insight and clinical translation.Frontiers in immunology · 2026Review
- Dissection Propagation via Avalanches in Human Descending Thoracic Aorta: Effect of Aging.Acta biomaterialia · 2025Article
- Why are soft collagenous tissues so tough?Science advances · 2025Article
- Mechanisms of aortic dissection: From pathological changes to experimental andProgress in materials science · 2025Article
- A multiscale discrete fiber model of failure in heterogeneous tissues: Applications to remodeled cerebral aneurysms.Journal of biomechanics · 2025Article
- Traction-separation law parameters for the description of age-related changes in the delamination strength of the human descending thoracic aorta.Biomechanics and modeling in mechanobiology · 2024Article
- A morphological indicator for aortic dissection: fitting circle of the thoracic aorta.BMC cardiovascular disorders · 2024Article
- Article
- Roles of pyroptosis and immune infiltration in aortic dissection.Frontiers in molecular biosciences · 2024Article
- Traumatic Aortic Dissection as a Unique Clinical Entity: A Single-Center Retrospective Study.Journal of clinical medicine · 2023Article
- Mathematical modeling and numerical simulation of arterial dissection based on a novel surgeon's view.Biomechanics and modeling in mechanobiology · 2023Article
- Delamination Strength and Elastin Interlaminar Fibers Decrease with the Development of Aortic Dissection in Model Rats.Bioengineering (Basel, Switzerland) · 2023Article
- Mechanistic insight into lysyl oxidase in vascular remodeling and angiogenesis.Genes & diseases · 2023Review
- A discrete fiber network finite element model of arterial elastin network considering inter-fiber crosslinking property and density.Journal of the mechanical behavior of biomedical materials · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Aortic dissection is a devastating cardiovascular disease known for its rapid propagation and high morbidity and mortality. The mechanisms underlying the propagation of aortic dissection are not well understood. Our study reports the discovery of avalanche-like failure of the aorta during dissection propagation that results from the local buildup of strain energy followed by a cascade failure of inhomogeneously distributed interlamellar collagen fibers. An innovative computational model was developed that successfully describes the failure mechanics of dissection propagation. Our study provides the first quantitative agreement between experiment and model prediction of the dissection propagation within the complex extracellular matrix (ECM). Our results may lead to the possibility of predicting such catastrophic events based on microscopic features of the ECM.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.