Evidence map›Paper›PMID 32494673›Full record

ArticleScience advances2020

Graphene quantum dots as anti-inflammatory therapy for colitis.

Byung-Chul Lee, Jin Young Lee, Juhee Kim, Je Min Yoo, Insung Kang, Jae-Jun Kim, Nari Shin, Dong Jin Kim, Soon Won Choi, Donghoon Kim and 2 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 136 citations in OpenAlex.

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  11. Therapeutic Potential of Graphene Quantum Dots on Pterygium Cells.Investigative ophthalmology & visual science · 2025
    Article
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  13. Review
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Byung-Chul LeeAdult Stem Cell Research Center and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0003-0358-6855
Jin Young LeeAdult Stem Cell Research Center and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-8559-7077
Juhee KimDepartment of Chemistry, College of Natural Sciences, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-3977-8501
Je Min YooDepartment of Chemistry, College of Natural Sciences, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0003-3074-859X
Insung KangAdult Stem Cell Research Center and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0003-1792-5002
Jae-Jun KimAdult Stem Cell Research Center and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-8948-4501
Nari ShinAdult Stem Cell Research Center and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-6848-0368
Dong Jin KimProgram in Nano Science and Technology, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.
Soon Won ChoiAdult Stem Cell Research Center and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-8642-6093
Donghoon KimBiographene Inc., Advanced Institute of Convergence Technology, Suwon 16229, Republic of Korea.
Byung Hee HongDepartment of Chemistry, College of Natural Sciences, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-8355-8875
Kyung-Sun KangAdult Stem Cell Research Center and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-9322-741X
Seoul National University · KRAdvanced Institute of Convergence Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While graphene and its derivatives have been suggested as a potential nanomedicine in several biomimetic models, their specific roles in immunological disorders still remain elusive. Graphene quantum dots (GQDs) may be suitable for treating intestinal bowel diseases (IBDs) because of their low toxicity in vivo and ease of clearance. Here, GQDs are intraperitoneally injected to dextran sulfate sodium (DSS)-induced chronic and acute colitis model, and its efficacy has been confirmed. In particular, GQDs effectively prevent tissue degeneration and ameliorate intestinal inflammation by inhibiting T

Identifiers

PMID32494673
PMCPMC7190325
OpenAlexW3021857066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.