ArticleScience advances2020
STING couples with PI3K to regulate actin reorganization during BCR activation.
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Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
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Who cites it
22 citing papers in PubMed, 32 citations in OpenAlex.
- Profilin-1 Deficiency Activates STING to Drive T Cell-Mediated Anti-Tumor Immunity in Breast Cancer.bioRxiv : the preprint server for biology · 2026Article
- Ring finger protein 213 regulates B-cell receptor signaling, metabolism, and development in B lymphocytes.Signal transduction and targeted therapy · 2026Article
- STING deficiency alleviates scar formation after glaucoma filtration surgery by suppressing p38 MAPK-induced inflammation in mice.Eye and vision (London, England) · 2026Article
- Elastic Cytomatrix Dynamics Influences Metabolic Rate and Tumor Microenvironment Formation.Cancers · 2025Review
- MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axis.Cell death & disease · 2025Article
- DDIT3 deficiency ameliorates systemic lupus erythematosus by regulating B cell activation and differentiation.Life medicine · 2025Article
- MAPK4 inhibits the early aberrant activation of B cells in rheumatoid arthritis by promoting the IRF4-SHIP1 signaling pathway.Cell death & disease · 2025Article
- Mitochondria-associated endoplasmic reticulum membrane (MAM): a dark horse for diabetic cardiomyopathy treatment.Cell death discovery · 2024Review
- Immune-related gene characterization and biological mechanisms in major depressive disorder revealed based on transcriptomics and network pharmacology.Frontiers in psychiatry · 2024Article
- Single-cell transcriptome analysis profiles the expression features of TMEM173 in BM cells of high-risk B-cell acute lymphoblastic leukemia.BMC cancer · 2023Article
- STING controls T cell memory fitness during infection through T cell-intrinsic and IDO-dependent mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Identification of shared gene signatures and molecular mechanisms between chronic kidney disease and ulcerative colitis.Frontiers in immunology · 2023Article
- Unexpected Breg-NK crosstalk in STING agonist therapy.Cellular & molecular immunology · 2022Article
- Involvement of MST1/mTORC1/STAT1 activity in the regulation of B-cell receptor signalling by chemokine receptor 2.Clinical and translational medicine · 2022Article
- A novel ten-gene prognostic signature for cervical cancer based on CD79B-related immunomodulators.Frontiers in genetics · 2022Article
- STING1 in Different Organelles: Location Dictates Function.Frontiers in immunology · 2022Review
- A preliminary study of KAT2A on cGAS-related immunity in inflammation amplification of systemic lupus erythematosus.Cell death & disease · 2021Article
- SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism.Signal transduction and targeted therapy · 2021Article
- STINGing the Tumor Microenvironment to Promote Therapeutic Tertiary Lymphoid Structure Development.Frontiers in immunology · 2021Review
- B Cell Intrinsic STING Signaling Is Not Required for Autoreactive Germinal Center Participation.Frontiers in immunology · 2021Article
Corrections and comments
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Authors and funding
18 authors at 8 institutions in 3 countries.
Yukai JingDepartment of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0001-6409-1157
Xin DaiDepartment of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-0310-4273
Lu YangDepartment of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0003-0595-6311
Danqing KangDepartment of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-4879-9005
Panpan JiangDepartment of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-2226-1709
Na LiDepartment of Immunology, School of Medicine, Yangtze University, Jingzhou, China.ORCID 0000-0002-0504-4753
Jiali ChengDepartment of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0003-3210-2522
Jingwen LiDepartment of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0003-1135-6611
Heather MillerDepartment of Intracellular Pathogens, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA.ORCID 0000-0002-4670-2855
Boxu RenDepartment of Immunology, School of Medicine, Yangtze University, Jingzhou, China.ORCID 0000-0002-3294-3260
Quan GongDepartment of Immunology, School of Medicine, Yangtze University, Jingzhou, China.ORCID 0000-0003-4094-7883
Wei YinWuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zheng LiuDepartment of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-4168-6702
Pieta K MattilaInstitute of Biomedicine, Unit of Pathology, and MediCity Research Laboratories, University of Turku, Turku, Finland.ORCID 0000-0003-2805-0686
Qin NingDepartment of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-2027-9593
Jinqiao SunDepartment of Clinical Immunology, Children's Hospital of Fudan University, Shanghai, China.
Bing YuDepartment of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0003-4365-2140
Chaohong LiuDepartment of Pathogen Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0001-7028-4625
Huazhong University of Science and Technology · CNYangtze University · CNTongji Hospital · CNCentral Hospital of Wuhan · CNChildren's Hospital of Fudan University · CNNational Institute of Allergy and Infectious Diseases · USUniversity of Turku · FIWuhan Children's Hospital · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
The adaptor protein, STING (stimulator of interferon genes), has been rarely studied in adaptive immunity. We used
Indexed as
ActinsReceptors, Antigen, B-CellAdaptor Proteins, Signal TransducingAnimalsAntigens, CD19HumansMiceMice, Inbred C57BLMice, KnockoutPhosphatidylinositol 3-KinasesActinsAdaptor Proteins, Signal TransducingAntigens, CD19Phosphatidylinositol 3-KinasesReceptors, Antigen, B-Cell
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.