ArticleScience advances2020
Molecular engineering of metal coordination interactions for strong, tough, and fast-recovery hydrogels.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Sustainable solar water purification: Exploring the structural advantages of higher plants.Science advances · 2026Article
- Amplified friction via a cooperative entanglement domains and steric hindrance for damping hydrogels.Nature communications · 2026Article
- Stimuli-Responsive Hydrogels in Food Sector: Multi-Component Design, Stimulus-Response Mechanisms, and Broad Applications.Gels (Basel, Switzerland) · 2026Review
- Photochemical nanomotors reverse anxiety- and depressive-related behaviors in rodents via spatiotemporal polarity dynamics tuning.Nature communications · 2026Article
- Hierarchical picot-fiber hydrogel coating with ultralow friction and high wear resistance.Nature communications · 2026Article
- A Review on Recent Progress and Clinical Translation of Self-Assembled Hydrogels in Diabetic Wound Repair.International journal of nanomedicine · 2026Review
- Mussel-Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self-Healing Properties.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Mechanoresponsive Hydrogels Emerging from Dynamic and Non-Covalent Interactions.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Ultra-Low Hysteresis Under Large Deformation Enabled by Fast Chains Relaxation in Highly Competitive Dynamic Hydrogen Bond Networks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Spiers Memorial Lecture: Recent advances (and challenges) in supramolecular gels.Faraday discussions · 2025Article
- Enzyme-Triggered Formation of Tensegrity Structures for Mechanospatial Manipulation of Hydrogels.Gels (Basel, Switzerland) · 2025Article
- Alkaline Amino Acids for Salt Reduction in Surimi: A Review.Foods (Basel, Switzerland) · 2025Review
- A tough and robust hydrogel constructed through carbon dots induced crystallization domains integrated orientation regulation.Nature communications · 2025Article
- Hydrogels with prestressed tensegrity structures.Nature communications · 2025Article
- Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network.Nature communications · 2025Article
- Protein-based double-network hydrogels mimicking oral mucosa.Frontiers in chemistry · 2025Article
- Hydrogel-Based Strategies for Liver Tissue Engineering.Chem & bio engineering · 2024Review
- Rapidly damping hydrogels engineered through molecular friction.Nature communications · 2024Article
- Lysine-Triggered Polymeric Hydrogels with Self-Adhesion, Stretchability, and Supportive Properties.Polymers · 2024Article
- A mechanical-assisted post-bioprinting strategy for challenging bone defects repair.Nature communications · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many load-bearing tissues, such as muscles and cartilages, show high elasticity, toughness, and fast recovery. However, combining these mechanical properties in the same synthetic biomaterials is fundamentally challenging. Here, we show that strong, tough, and fast-recovery hydrogels can be engineered using cross-linkers involving cooperative dynamic interactions. We designed a histidine-rich decapeptide containing two tandem zinc binding motifs. Because of allosteric structural change-induced cooperative binding, this decapeptide had a higher thermodynamic stability, stronger binding strength, and faster binding rate than single binding motifs or isolated ligands. The engineered hybrid network hydrogels containing the peptide-zinc complex exhibit a break stress of ~3.0 MPa, toughness of ~4.0 MJ m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.