Evidence map›Paper›PMID 32494605›Full record

ArticleScience advances2020

Electro-actuated valves and self-vented channels enable programmable flow control and monitoring in capillary-driven microfluidics.

Yulieth Arango, Yuksel Temiz, Onur Gökçe, Emmanuel Delamarche

Abstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Microfluidic valves for wearable sweat analysis: a review.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Review
  2. Article
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  8. Reconfigurable microfluidics.Nature reviews. Chemistry · 2022
    Review
  9. Capillaric field effect transistors.Microsystems & nanoengineering · 2022
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yulieth ArangoIBM Research-Zurich, 8803-Rüschlikon, Switzerland.ORCID 0000-0001-9042-3952
Yuksel TemizIBM Research-Zurich, 8803-Rüschlikon, Switzerland.ORCID 0000-0001-9286-7864
Onur GökçeIBM Research-Zurich, 8803-Rüschlikon, Switzerland.ORCID 0000-0002-3913-3893
Emmanuel DelamarcheIBM Research-Zurich, 8803-Rüschlikon, Switzerland.ORCID 0000-0002-8753-8895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microfluidics are essential for many lab-on-a-chip applications, but it is still challenging to implement a portable and programmable device that can perform an assay protocol autonomously when used by a person with minimal training. Here, we present a versatile concept toward this goal by realizing programmable liquid circuits where liquids in capillary-driven microfluidic channels can be controlled and monitored from a smartphone to perform various advanced tasks of liquid manipulation. We achieve this by combining electro-actuated valves (e-gates) with passive capillary valves and self-vented channels. We demonstrate the concept by implementing a 5-mm-diameter microfluidic clock, a chip to control four liquids using 100 e-gates with electronic feedback, and designs to deliver and merge multiple liquids sequentially or in parallel in any order and combination. This concept is scalable, compatible with high-throughput manufacturing, and can be adopted in many microfluidics-based assays that would benefit from precise and easy handling of liquids.

Identifiers

PMID32494605
PMCPMC7250678

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.