Evidence map›Paper›PMID 32494581›Full record

ArticleOpen forum infectious diseases2020

Case Report: Successful Rescue Therapy of Extensively Drug-Resistant

Michael Dagher, Felicia Ruffin, Steven Marshall, Magdalena Taracila, Robert A Bonomo, Rachel Reilly, Vance G Fowler, Joshua T Thaden

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Comprehensive Approaches to CombattingAntibiotics (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Carbapenem-ResistantOpen forum infectious diseases · 2023
    Article
  11. [Clinical experience using cefiderocol].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2023
    Review
  12. The Role of Novel Antibiotics in the Management of Diabetic Foot Infection.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
    Review
  13. The role of cefiderocol in clinical practice.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  14. Clinical experience of cefiderocol.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  15. Review
  16. Cefiderocol: A New Cephalosporin Stratagem Against Multidrug-Resistant Gram-Negative Bacteria.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Review
  17. Review
  18. New Perspectives on Antimicrobial Agents: Cefiderocol.Antimicrobial agents and chemotherapy · 2021
    Review
  19. Article
  20. JAC-antimicrobial resistance · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Michael DagherDivision of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Felicia RuffinDivision of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Steven MarshallLouis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
Magdalena TaracilaLouis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
Robert A BonomoLouis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
Rachel ReillyDepartment of Orthopedic Surgery, Duke University School of Medicine, Durham, North Carolina, USA.
Vance G FowlerDivision of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Joshua T ThadenDivision of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Duke University · USLouis Stokes Cleveland VA Medical Center · USCase Western Reserve University · US

Funding

Mentoring Patient Oriented Research in Antibiotic-Resistant BacteriaK24AI093969 · NIAID · DUKE UNIVERSITY · PI FOWLER, VANCE G. · 2011 to 2020
$1.6M
NIAID NIH HHS K24 AI093969
6 · The paper itself

Abstract

Cefiderocol is a novel catechol siderophore cephalosporin antibiotic developed to treat resistant gram-negative infections. We describe its successful use as rescue therapy, combined with surgical debridement, to treat a patient with osteomyelitis due to extensively drug-resistant

Indexed as

Acinetobacter baumanniiantimicrobial resistancecefiderocolosteomyelitis

Identifiers

PMID32494581
PMCPMC7252278
OpenAlexW3023693376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.