Evidence map›Paper›PMID 32494071›Full record

ArticleNature2020

Multilayered mechanisms ensure that short chromosomes recombine in meiosis.

Hajime Murakami, Isabel Lam, Pei-Ching Huang, Jacquelyn Song, Megan van Overbeek, Scott Keeney

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 75 citations in OpenAlex.

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  18. Reconstitution of SPO11-dependent double-strand break formation.bioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hajime MurakamiMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. murakamh@mskcc.org.
Isabel LamMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Pei-Ching HuangMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jacquelyn SongMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Megan van OverbeekMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Scott KeeneyMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. s-keeney@ski.mskcc.org.ORCID http://orcid.org/0000-0002-1283-6417
Memorial Sloan Kettering Cancer Center · USBrigham and Women's Hospital · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Mechanism and regulation of meiotic recombinationR35GM118092 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Scott Keeney · 2016 to 2026
$7.0M
Mechanism of meiotic recombination in yeastR01GM058673 · NIGMS · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI KEENEY, SCOTT · 1999 to 2015
$6.0M
The Role of Chromatin Architecture in Programmed Double-Strand BreaksF32GM096692 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI VAN OVERBEEK, MEGAN ELIZABETH · 2011 to 2012
$109k
Functional Characterization of Rec104 in Meiotic RecombinationF31GM097861 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI LAM, ISABEL · 2011 to 2012
$84k
NCI NIH HHS P30 CA008748NIGMS NIH HHS F31 GM097861NIGMS NIH HHS F32 GM096692NIGMS NIH HHS R01 GM058673NIGMS NIH HHS R35 GM118092
6 · The paper itself

Abstract

In most species, homologous chromosomes must recombine in order to segregate accurately during meiosis

Indexed as

Homologous RecombinationMeiosisCentromereChromosome SegregationChromosomes, FungalDNA Breaks, Double-StrandedDNA Replication TimingMeiotic Prophase IRecombinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTelomereTime FactorsREC107 protein, S cerevisiaeREC114 protein, S cerevisiaeRecombinasesSaccharomyces cerevisiae Proteins

Identifiers

PMID32494071
PMCPMC7298877
OpenAlexW3022715769

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.