ArticleScientific reports2020
Frontoparietal structural properties mediate adult life span differences in executive function.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Characterizing Resting-State Frontoparietal-Amygdala Network Connectivity as a Potential Moderator of the Developmental Link Between Executive Functioning and Internalizing Symptoms: A Group Iterative Multiple Model Estimation-Based Approach.Biological psychiatry global open science · 2026Article
- Neuroimaging Correlates of the NIH Toolbox Cognition and Trail Making Tests: Normative Benchmarks in Healthy Aging.Clinical and translational neuroscience · 2026Article
- Association between processing speed and segregation/integration of large-scale functional networks in middle-aged and older people living with HIV.BMC neurology · 2026Article
- Insight and executive functions in acquired brain injury: empirical evidence and theoretical frameworks.Frontiers in neurology · 2026Review
- Different structural brain patterns and their association with executive function and general cognitive ability in cognitively normal elderly adults.Frontiers in aging neuroscience · 2026Article
- Cognitive and Neurobiological Correlates for Switching/Inhibition Moderate the Relations Between Word Reading and Reading Comprehension in Hebrew-Speaking Children: An fMRI Study.Dyslexia (Chichester, England) · 2025Article
- Detecting cognitive decline in high-functioning older adults: The relationship between subjective cognitive concerns, frequency of high neuropsychological test scores, and the frontoparietal control network.Journal of the International Neuropsychological Society : JINS · 2024Article
- The role of attitudes towards contradiction in psychological resilience: the cortical mechanism of conflicting resolution networks.Scientific reports · 2024Article
- Brain topology underlying executive functions across the lifespan: focus on the default mode network.Frontiers in psychology · 2024Article
- Characterization of the angular gyrus in an older adult population: a multimodal multilevel approach.Brain structure & function · 2023Article
- Graph analysis of cortical reorganization after virtual reality-based rehabilitation following stroke: a pilot randomized study.Frontiers in neurology · 2023Article
- Maternal age differences in cognitive regulation: examination of associations and interactions between RSA and EEG frontoparietal alpha power coherence.Frontiers in human neuroscience · 2023Article
- Understanding cognitive control in aging: A brain network perspective.Frontiers in aging neuroscience · 2022Review
- Two-Year Follow-Up Study of the Relationship Between Brain Structure and Cognitive Control Function Across the Adult Lifespan.Frontiers in aging neuroscience · 2021Article
- The effects of transcranial magnetic stimulation on cognitive flexibility among undergraduates with insomnia symptoms: A prospective, single-blind, randomized control trial.International journal of clinical and health psychology : IJCHPArticle
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4 authors.
Funding
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Abstract
Executive function (EF) refers to a set of cognitive functions that support goal-directed behaviors. Recent findings have suggested that the frontoparietal network (FPN) subserves neural processes that are related to EF. However, the FPN structural and functional network properties that mediate age-related differences in EF components remain unclear. To this end, we used three experimental tasks to test the component processes of EF based on Miyake and Friedman's model: one common EF component process (incorporating inhibition, shifting, and updating) and two specific EF component processes (shifting and updating). We recruited 126 healthy participants (65 females; 20 to 78 years old) who underwent both structural and functional MRI scanning. We tested a mediation path model of three structural and functional properties of the FPN (i.e., gray matter volume, white matter fractional anisotropy, and intra/internetwork functional connectivity) as mediators of age-related differences in the three EF components. The results indicated that age-related common EF component differences are mediated by regional gray matter volume changes in both hemispheres of the frontal lobe, which suggests that structural changes in the frontal lobe may have an indirect influence on age-related general elements of EF. These findings suggest that the FPN mediates age-related differences in specific components of EF.
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