Evidence map›Paper›PMID 32493968›Full record

ArticleScientific reports2020

Serological and molecular detection of Neospora caninum and Toxoplasma gondii in human umbilical cord blood and placental tissue samples.

Pâmella Oliveira Duarte, Leandra Marla Oshiro, Namor Pinheiro Zimmermann, Bárbara Guimarães Csordas, Doroty Mesquita Dourado, Jacqueline Cavalcante Barros, Renato Andreotti

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. High occurrence of anti-Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2026
    Article
  3. Evidence of in Utero Anti-Microorganisms · 2026
    Article
  4. Article
  5. Review
  6. First report ofJournal of advanced veterinary and animal research · 2024
    Article
  7. Article
  8. Seroprevalence ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  9. Seropositivity of Anti-Tropical medicine and infectious disease · 2023
    Article
  10. Molecular detection of Toxoplasma gondii, Neospora caninum and Sarcocystis spp in tissues of Sus scrofa slaughtered in southern Brazil.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2023
    Article
  11. Article
  12. Review
  13. Seroprevalence of Specific Antibodies toAnimals : an open access journal from MDPI · 2022
    Article
  14. Prevalence ofPathogens (Basel, Switzerland) · 2022
    Article
  15. Apicomplexans in Goat: Prevalence ofAnimals : an open access journal from MDPI · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Seroepidemiology ofVeterinary medicine (Auckland, N.Z.) · 2022
    Article
  20. Occurrence of Toxoplasma gondii and Neospora caninum antibodies and risk factors in domiciliated dogs of Manaus, Amazonas, Brazil.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pâmella Oliveira DuartePrograma de Pós-Graduação em Doenças Infecciosas e Parasitárias- Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS, Brasil.
Leandra Marla OshiroLaboratório de Biologia Molecular do Carrapato, Departamento de Sanidade Animal, Embrapa Gado de Corte, Campo Grande, MS, Brasil.
Namor Pinheiro ZimmermannProfessor do Curso de Medicina Veterinária do Centro Universitário da Grande Dourados-UNIGRAN, Dourados, Brasil.
Bárbara Guimarães CsordasBolsista de Pós-Doutorado- FUNDAPAM, Laboratório de Biologia Molecular do Carrapato, Departamento de Sanidade Animal, Embrapa Gado de Corte, Campo Grande, MS, Brasil.
Doroty Mesquita DouradoLaboratório de Toxonologia e Plantas Medicinais-Uniderp Agrárias, Campo Grande, Brasil.
Jacqueline Cavalcante BarrosEmpresa Brasileira de Pesquisa Agropecuária, Embrapa Gado de Corte, Campo Grande, MS, Brasil.
Renato AndreottiEmpresa Brasileira de Pesquisa Agropecuária, Embrapa Gado de Corte, Campo Grande, MS, Brasil. renato.andreotti@embrapa.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neosporosis primarily affects cattle and dogs and is not currently considered a zoonotic disease. Toxoplasmosis is a zoonosis with a worldwide distribution that is asymptomatic in most cases, but when acquired during pregnancy, it can have serious consequences. The seropositivity rates determined by the indirect fluorescent antibody test for Neospora caninum (N. caninum) and Toxoplasma gondii (T. gondii) were 24.3% (49 samples) and 26.8% (54 samples), respectively. PCR positivity for N. caninum was observed in two samples of cord blood (1%) using the Nc5 and ITS1 gene, positivity for T. gondii was observed in 16 samples using the primer for the B1 gene (5.5% positivity in cord blood and 2.5% positivity in placental tissue). None of the samples showed structures characteristic of tissue cysts or inflammatory infiltrate on histopathology. Significant associations were observed only between N. caninum seropositivity and the presence of domestic animals (p = 0.039) and presence of dogs (p = 0.038) and between T. gondii seropositivity and basic sanitation (p = 0.04). This study obtained important findings regarding the seroprevalence and molecular detection of N. caninum and T. gondii in pregnant women; however, more studies are necessary to establish a correlation between risk factors and infection.

Indexed as

AdultAntibodies, ProtozoanBrazilCoccidiosisEnzyme-Linked Immunosorbent AssayFemaleFetal BloodFluorescent Antibody Technique, IndirectHumansNeosporaPlacentaPregnancySeroepidemiologic StudiesToxoplasmaToxoplasmosisAntibodies, Protozoan

Identifiers

PMID32493968
PMCPMC7271125

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.