Evidence map›Paper›PMID 32493965›Full record

ArticleNature communications2020

Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle.

Brendan Chestnut, Satish Casie Chetty, Andrew L Koenig, Saulius Sumanas

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 58 citations in OpenAlex.

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  13. Transgenic IDH2Oncogene · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brendan Chestnut *Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.
Satish Casie Chetty *Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.
Andrew L Koenig *Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.ORCID http://orcid.org/0000-0003-4384-1267
Saulius SumanasDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA. saulius.sumanas@cchmc.org.ORCID http://orcid.org/0000-0002-8605-6122
Cincinnati Children's Hospital Medical Center · US

Funding

THE ROLE OF COLLAGEN COL22A1 IN INTRACRANIAL ANEURYSMS AND VASCULAR STABILITYR01HL134815 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI SUMANAS, SAULIUS · 2017 to 2020
$1.8M
Characterization of a novel hematopoietic siteR21AI128445 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI SUMANAS, SAULIUS · 2017 to 2018
$429k
Identification of a novel population of hematopoietic precursor cellsF31HL135986 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI KOENIG, ANDREW LEIGHTON · 2017 to 2017
$21k
NHLBI NIH HHS F31 HL135986NHLBI NIH HHS R01 HL134815NIAID NIH HHS R21 AI128445
6 · The paper itself

Abstract

Cell fate decisions involved in vascular and hematopoietic embryonic development are still poorly understood. An ETS transcription factor Etv2 functions as an evolutionarily conserved master regulator of vasculogenesis. Here we report a single-cell transcriptomic analysis of hematovascular development in wild-type and etv2 mutant zebrafish embryos. Distinct transcriptional signatures of different types of hematopoietic and vascular progenitors are identified using an etv2

Indexed as

Gene Expression ProfilingSingle-Cell AnalysisAnimalsAnimals, Genetically ModifiedBiomarkersBlood VesselsCell DifferentiationCell MovementEmbryo, NonmammalianFibroblast Growth FactorsGreen Fluorescent ProteinsHeat-Shock ResponseModels, BiologicalMuscle, SkeletalMutationSomitesBiomarkersEtv2 protein, zebrafishFibroblast Growth FactorsGreen Fluorescent ProteinsZebrafish Proteins

Identifiers

PMID32493965
PMCPMC7271194
OpenAlexW3028667313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.