Evidence map›Paper›PMID 32493916›Full record

ArticleNature communications2020

Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases.

Tengfei Liu, Bowen Xiao, Fei Xiang, Jianglin Tan, Zhuo Chen, Xiaorong Zhang, Chengzhou Wu, Zhengwei Mao, Gaoxing Luo, Xiaoyuan Chen and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 275 papers.

0numbers the graph read from it
0cells of the map it votes in
275citing papers in PubMed
32.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

275 citing papers in PubMed, 831 citations in OpenAlex.

  1. Trial
  2. A bilayer hydrogel with a lower layer ROS-responsive Au-CeOInternational journal of pharmaceutics: X · 2026
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215 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Tengfei LiuInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), 400038, Chongqing, China.
Bowen XiaoInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), 400038, Chongqing, China.
Fei XiangInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), 400038, Chongqing, China.
Jianglin TanInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), 400038, Chongqing, China.
Zhuo ChenDepartment of Endocrinology, Southwest Hospital, Third Military Medical University (Army Medical University), 400038, Chongqing, China.
Xiaorong ZhangInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), 400038, Chongqing, China.
Chengzhou WuDepartment of Respiratory Care, Wuxi County People's Hospital, 405800, Chongqing, China.
Zhengwei MaoInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), 400038, Chongqing, China. zwmao@zju.edu.cn.ORCID http://orcid.org/0000-0001-7990-2856
Gaoxing LuoInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), 400038, Chongqing, China. logxw@hotmail.com.
Xiaoyuan ChenLaboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, 20892, USA. shawn.chen@nih.gov.ORCID http://orcid.org/0000-0002-9622-0870
Jun DengInstitute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Chongqing Key Laboratory for Disease Proteomics, Third Military Medical University (Army Medical University), 400038, Chongqing, China. djun.123@163.com.
Army Medical University · CNNational Institutes of Health · US

Funding

Laboratory of Molecular Imaging and NanomedicineZIAEB000073 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI CHEN, XIAOYUAN · 2010 to 2020
$32.8M
Intramural NIH HHS ZIA EB000073
6 · The paper itself

Abstract

Oxidative stress is associated with many acute and chronic inflammatory diseases, yet limited treatment is currently available clinically. The development of enzyme-mimicking nanomaterials (nanozymes) with good reactive oxygen species (ROS) scavenging ability and biocompatibility is a promising way for the treatment of ROS-related inflammation. Herein we report a simple and efficient one-step development of ultrasmall Cu

Indexed as

Particle SizeAcute Kidney InjuryAlanine TransaminaseAnimalsAntioxidantsAspartate AminotransferasesCattleCopperFemaleFree Radical ScavengersHEK293 CellsHumansInflammationMiceMice, Inbred BALB CMice, Inbred C57BLAlanine TransaminaseAntioxidantsAspartate AminotransferasesCopperFree Radical ScavengersReactive Oxygen Species

Identifiers

PMID32493916
PMCPMC7270130
OpenAlexW3028618163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.