ArticleGut2021
Epidemiology and outcomes of gastroparesis, as documented in general practice records, in the United Kingdom.
Article in Gut, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06340217 (The Efficacy and Safety of WMT in the Treatment of Diabetic Gastroparesis), which is not on this map. Cited by 49 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Efficacy and Safety of WMT in the Treatment of Diabetic Gastroparesis: A Multicenter, Randomized, Double-blind, Placebo-controlled Study
Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 130 citations in OpenAlex.
- A bibliometric analysis of diabetic gastroparesis from 1979 to 2024.Frontiers in medicine · 2024Pooled it
- Prevalence of gastroparesis in diabetic patients: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Risk of Adverse Events Associated with Domperidone and Metoclopramide in Gastroparesis: Systematic Review and Meta-analysis.Drugs in R&D · 2023Pooled it
- Pooled it
- Safety, Pharmacokinetics, and Pharmacodynamics of Trazpiroben (TAK-906), a Novel Selective DClinical pharmacology in drug development · 2021Trial
- Development and validation of a rapid 15-minute gastric ultrasound protocol for suspected gastroparesis: a prospective diagnostic accuracy study.Annals of medicine · 2026Article
- Exploring Clinical Similarities and Distinctions Between Gastroparesis and Functional Dyspepsia: A Propensity-Matched Cohort Study.Neurogastroenterology and motility · 2026Observational
- Gastroparesis in heart failure: temporal trends, clinical correlates, and outcomes in a large national cohort.Translational gastroenterology and hepatology · 2026Article
- Efficacy and safety of tangweian recipe in the treatment of diabetic gastroparesis: a protocol for a non-inferiority, double-blind, active drug, randomized controlled clinical trial.BMC complementary medicine and therapies · 2025Article
- Gastric ultrasound: Enhancing preoperative risk assessment and patient safety.Journal of perioperative practice · 2025Article
- Can Symptoms Predict Delayed Gastric Emptying in Diabetic Patients: A Multicenter Study to Revisit Gastroparesis.Journal of neurogastroenterology and motility · 2025Article
- Gastroparesis and its Nutritional Implications.Current gastroenterology reports · 2025Review
- Functional constipation is associated with long-term clinical failure after gastric per-oral endoscopic myotomy for the treatment of gastroparesis.Surgical endoscopy · 2025Observational
- Pharmacologic treatments for gastroparesis.Pharmacological reviews · 2025Review
- Medication reconciliation enhances the accuracy of gastric emptying scintigraphy.EJNMMI radiopharmacy and chemistry · 2024Article
- The presentation of two rare idiopathic diseases in one patient: spontaneous idiopathic pneumoperitoneum and idiopathic gastroparesis: a case report.Annals of medicine and surgery (2012) · 2024Article
- Seven-Year Experience of Intramural Surgery in the Middle East: A Safety and Feasibility Analysis.Journal of clinical medicine · 2024Article
- Common Pathophysiological Mechanisms and Treatment of Diabetic Gastroparesis.Journal of neurogastroenterology and motility · 2024Review
- Gut Bacteria Provide Genetic and Molecular Reporter Systems to Identify Specific Diseases.International journal of molecular sciences · 2024Review
- Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo generate real-world evidence for the epidemiology of gastroparesis in the UK, we evaluated the prevalence, incidence, patient characteristics and outcomes of gastroparesis in the Clinical Practice Research Datalink (CPRD) database.
designThis was a retrospective, cross-sectional study. Prevalence and incidence of gastroparesis were evaluated in the CPRD database, with linkage to Hospital Episodes Statistics Admitted Patient Care and Office for National Statistics mortality data. Prevalence and incidence were age and sex standardised to mid-2017 UK population estimates. Descriptive analyses of demographics, aetiologies, pharmacological therapies and mortality were conducted.
resultsStandardised prevalence of gastroparesis, as documented in general practice records, was 13.8 (95% CI 12.6 to 15.1) per 100 000 persons in 2016, and standardised incidence of gastroparesis rose from 1.5 (95% CI 1.1 to 1.8) per 100 000 person-years in 2004 to 1.9 (95% CI 1.4 to 2.3) per 100 000 person-years in 2016. The most common disease aetiologies were idiopathic (39.4%) and diabetic gastroparesis (37.5%), with a similar distribution of type 1 and type 2 diabetes among the 90% who had type of diabetes documented. Patients with diabetic gastroparesis had a significantly higher risk of mortality than those with idiopathic gastroparesis after diagnosis (adjusted HR 1.9, 95% CI 1.2 to 3.0). Of those with gastroparesis, 31.6% were not offered any recognised pharmacological therapy after diagnosis.
conclusionThis is, to our knowledge, the first population-based study providing data on epidemiology and outcomes of gastroparesis in Europe. Further research is required to fully understand the factors influencing outcomes and survival of patients with gastroparesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.