Evidence map›Paper›PMID 32493450›Full record

ArticleBMC nephrology2020

Sedentary behaviour, physical activity, and renal function in older adults: isotemporal substitution modelling.

Keisei Kosaki, Koichiro Tanahashi, Masahiro Matsui, Nobuhiko Akazawa, Yosuke Osuka, Kiyoji Tanaka, David W Dunstan, Neville Owen, Ai Shibata, Koichiro Oka and 1 more

Abstract read
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Examining the Links Between Physical Activity, Sitting Time, and Renal Function in T2DM Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
  16. Article
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  18. Multicomponent Physical Exercise Training in Multimorbid and Palliative Oldest Adults.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Keisei KosakiFaculty of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan.
Koichiro TanahashiDepartment of Health and Sports Sciences, Kyoto Pharmaceutical University, Kyoto, Kyoto, Japan.
Masahiro MatsuiGraduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Nobuhiko AkazawaJapan Institute of Sports Sciences, Kita-ku, Tokyo, Japan.
Yosuke OsukaResearch Team for Promoting Independence of the Elderly, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan.
Kiyoji TanakaFaculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.
David W DunstanBaker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Neville OwenBaker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Ai ShibataFaculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Koichiro OkaFaculty of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan.
Seiji MaedaFaculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan. maeda.seiji.gn@u.tsukuba.ac.jp.ORCID 0000-0003-1642-4644

Funding

Japan Society for the Promotion of Science 19H03995Japan Society for the Promotion of Science 19J01099
6 · The paper itself

Abstract

backgroundPhysical inactivity and sedentary behaviour (too much sitting) can contribute to renal dysfunction. However, the potential benefits of behavioural change (e.g. replacing sedentary behaviour with physical activity) on renal function are not well understood. We used isotemporal substitution to model potential impacts of behaviours on renal function by replacing time spent in one behaviour to another.

methodsIn 174 older Japanese adults (age, 50-83 years; females, 76%), the time spent in sedentary behaviour, light-intensity physical activity (LPA), and moderate- to vigorous-intensity physical activity (MVPA) were assessed using an uniaxial accelerometer. Renal function was evaluated by the estimated glomerular filtration rate (eGFR) from serum creatinine and cystatin C levels.

resultsIn univariate analyses, eGFR was significantly, albeit weakly, correlated with time spent in sedentary behaviour (r

conclusionsThese cross-sectional findings suggest that sedentary behaviour (detrimentally) and physical activity (beneficially) may affect renal function and that replacing sedentary behaviour with MVPA may benefit renal health in older adults.

Indexed as

Sedentary BehaviorAccelerometryAgedAged, 80 and overCreatinineCross-Sectional StudiesCystatin CExerciseFemaleGlomerular Filtration RateHumansKidneyMaleMiddle AgedTime FactorsCreatinineCystatin CChronic kidney diseaseEstimated glomerular filtration rateIsotemporal substitution modellingPhysical activity timeSedentary time

Identifiers

PMID32493450
PMCPMC7268521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.