ArticleJournal of neuroinflammation2020
Exploration of anti-inflammatory mechanism of forsythiaside A and forsythiaside B in CuSO
Article in Journal of neuroinflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Efficacy ofFrontiers in pharmacology · 2024Pooled it
- Forsythiaside A inhibits progression and induces autophagy in lung adenocarcinoma: an integrated study combining network pharmacology and experimental validation.Scientific reports · 2026Article
- Forsythiaside A Ameliorates Inflammation by Regulating the Autophagy in Methotrexate-induced Intestinal Mucositis.Combinatorial chemistry & high throughput screening · 2026Article
- Zebrafish as a multimodal platforms for anti-inflammatory phytomedicine discovery and translation.Frontiers in pharmacology · 2026Review
- LSD1 inhibition sensitizes anti-PD1 blockade immunotherapy by inhibiting the long-range attack of tumor-derived extracellular vesicles.Acta pharmaceutica Sinica. B · 2025Article
- WDR3 undergoes phase separation to mediate the therapeutic mechanism of Nilotinib against osteosarcoma.Journal of experimental & clinical cancer research : CR · 2025Article
- Mesenchymal stem cells alleviate pulmonary fibrosis and gut microbiota dysbiosis in systemic sclerosis.Frontiers in microbiology · 2025Article
- Review
- Article
- A GC-MS-based untargeted metabolomics approach for comprehensive metabolic profiling of vancomycin-induced toxicity in mice.Heliyon · 2022Article
- Forsythiaside A improves Influenza A virus infection through TLR7 signaling pathway in the lungs of mice.BMC complementary medicine and therapies · 2022Article
- Anti-Inflammatory Effects and Mechanisms of Dandelion in RAW264.7 Macrophages and Zebrafish Larvae.Frontiers in pharmacology · 2022Article
- Forsythiaside A Regulates Activation of Hepatic Stellate Cells by Inhibiting NOX4-Dependent ROS.Oxidative medicine and cellular longevity · 2022Article
- Efficacy and Safety of Lianhua Qingke Tablets in the Treatment of Mild and Common-Type COVID-19: A Randomized, Controlled, Multicenter Clinical Study.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Forsythiasides: A review of the pharmacological effects.Frontiers in cardiovascular medicine · 2022Review
- Anti-Inflammatory and Antioxidant Properties ofEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Study on The Anti-Inflammatory Effects ofFrontiers in pharmacology · 2021Article
- Activation of Autophagy Through the NLRP3/mTOR Pathway: A Potential Mechanism for Alleviation of Pneumonia by QingFei Yin.Frontiers in pharmacology · 2021Article
- Comparative Evaluation ofFrontiers in pharmacology · 2021Article
- Forsythiasides-Rich Extract From Forsythiae Fructus Inhibits Mast Cell Degranulation by Enhancing Mitochondrial CaFrontiers in pharmacology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundInflammation is a general pathological phenomenon during severe disturbances to the homeostasis. Forsythiaside A (FA) and forsythiaside B (FB), isolated from the dried fruit of Forsythia suspensa (Thunb.) Vahl, are phenylethanoid compounds that show a significant anti-inflammatory effect. However, the properties and therapeutic mechanisms of this effect have not yet been systematically elucidated.
methodsIn this study, the anti-inflammatory effects of FA and FB were investigated in CuSO
resultsFA and FB inhibited neutrophils migration to the damaged neuromasts and remarkably reduced CuSO
conclusionsOur results indicate that FA and FB possess remarkable anti-inflammatory properties, protecting against CuSO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.