Evidence map›Paper›PMID 32493319›Full record

ArticleBMC health services research2020

Smart triage: triage and management of sepsis in children using the point-of-care Pediatric Rapid Sepsis Trigger (PRST) tool.

Alishah Mawji, Edmond Li, Clare Komugisha, Samuel Akech, Dustin Dunsmuir, Matthew O Wiens, Niranjan Kissoon, Nathan Kenya-Mugisha, Abner Tagoola, David Kimutai and 3 more

Registry-linked trialOpen access · goldAbstract readControlled Clinical TrialMulticenter Study
In one paragraph

Article in BMC health services research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04304235 (Smart Triage), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04304235 nacompletednot on this map

Smart Triage: Triage and Management of Sepsis in Children Using the Point-of-care Paediatric Rapid Sepsis Trigger (PRST) Tool

TypeinterventionalSponsorUniversity of British ColumbiaRan2020 to 2023Enrolled18,693ConditionsSepsis, InfectionArmsPediatric Rapid Sepsis Trigger (PRST) tool, Emergency Triage and Treatment (ETAT) guidelines
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
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  5. Tumour lysis syndrome.Nature reviews. Disease primers · 2024
    Review
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  8. Observational
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  14. A sepsis trigger tool reduces time to antibiotic administration in the NICU.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
  15. Scoping review of health information technology usability methods leveraged in Africa.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Alishah MawjiDepartment of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, 217-2176 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada. alishah.mawji@bcchr.ca.ORCID http://orcid.org/0000-0002-1591-947X
Edmond LiSchool of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, BC, V6T 1Z3, Canada.
Clare KomugishaWalimu, P.O. Box 9924, Plot 5-7, Coral Crescent, Kololo, Kampala, Uganda.
Samuel AkechKenya Medical Research Institute/Wellcome Trust Research Programme, P.O. Box 43640-00100, Nairobi, Kenya.
Dustin DunsmuirDigital Health Innovation Lab, BC Children's Hospital Research Institute, 948 W 28th Ave, Vancouver, BC, V5Z 4H4, Canada.
Matthew O WiensCenter for International Child Health, BC Children's Hospital Research Institute, 948 W 28th Ave, Vancouver, BC, V5Z 4H4, Canada.
Niranjan KissoonDepartment of Pediatrics, University of British Columbia, Rm B2W, 4480 Oak Street, Vancouver, BC, V6H 3V4, Canada.
Nathan Kenya-MugishaWalimu, P.O. Box 9924, Plot 5-7, Coral Crescent, Kololo, Kampala, Uganda.
Abner TagoolaJinja Reginal Referral Hospital, Jinja, Uganda.
David KimutaiMbagathi County Hospital, P.O. Box 20725-00202, Nairobi, Kenya.
Jeffrey N BoneDepartment of Obstetrics and Gynaecology, University of British Columbia, 1125 Howe Street, Vancouver, BC, V6Z 2K8, Canada.
Guy DumontElectrical and Computer Engineering, The University of British Columbia, 5500 - 2332 Main Mall, Vancouver, BC, V6T 1Z4, Canada.
J Mark AnserminoDepartment of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, 217-2176 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada.
University of British Columbia · CABC Children's Hospital · CAJinja Hospital · UGKenya Medical Research Institute · KENairobi Hospital · KE

Funding

Wellcome TrustWellcome Trust 215695/B/19/Z
6 · The paper itself

Abstract

backgroundSepsis is the leading cause of death and disability in children. Every hour of delay in treatment is associated with an escalating risk of morbidity and mortality. The burden of sepsis is greatest in low- and middle-income countries where timely treatment may not occur due to delays in diagnosis and prioritization of critically ill children. To circumvent these challenges, we propose the development and clinical evaluation of a digital triage tool that will identify high risk children and reduce time to treatment. We will also implement and clinically validate a Radio-Frequency Identification system to automate tracking of patients. The mobile platform (mobile device and dashboard) and automated patient tracking system will create a low cost, highly scalable solution for critically ill children, including those with sepsis.

methodsThis is pre-post intervention study consisting of three phases. Phase I will be a baseline period where data is collected on key predictors and outcomes before implementation of the digital triage tool. In Phase I, there will be no changes to healthcare delivery processes in place at the study hospitals. Phase II will involve model derivation, technology development, and usability testing. Phase III will be the intervention period where data is collected on key predictors and outcomes after implementation of the digital triage tool. The primary outcome, time to treatment initiation, will be compared to assess effectiveness of the digital health intervention. DISCUSSION: Smart technology has the potential to overcome the barrier of limited clinical expertise in the identification of the child at risk. This mobile health platform, with sensors and data-driven applications, will provide real-time individualized risk prediction to rapidly triage patients and facilitate timely access to life-saving treatments for children in low- and middle-income countries, where specialists are not regularly available and deaths from sepsis are common.

trial registrationClinical Trials.gov Identifier: NCT04304235, Registered 11 March 2020.

Indexed as

Digital TechnologyChildDelivery of Health CareDeveloping CountriesHospitalsHumansKenyaPoint-of-Care SystemsSepsisTelemedicineTriageUgandaDigital triage toolResource limited settingsSepsisTriage

Identifiers

PMID32493319
PMCPMC7268489
OpenAlexW3029221435

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.