Evidence map›Paper›PMID 32493273›Full record

Observational studyBMC endocrine disorders2020

Association between serum vitamin D and uric acid in the eastern Chinese population: a population-based cross-sectional study.

Yingchao Chen, Jing Cheng, Yi Chen, Ningjian Wang, Fangzhen Xia, Chi Chen, Bing Han, Yingli Lu

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC endocrine disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
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  7. Article
  8. Article
  9. Review
  10. Article
  11. The Relationship Between Hemoglobin Glycation Variation Index and Vitamin D in Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yingchao ChenInstitute and department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No.639 Zhizaoju Road, Shanghai, China.
Jing ChengInstitute and department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No.639 Zhizaoju Road, Shanghai, China.
Yi ChenInstitute and department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No.639 Zhizaoju Road, Shanghai, China.
Ningjian WangInstitute and department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No.639 Zhizaoju Road, Shanghai, China.
Fangzhen XiaInstitute and department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No.639 Zhizaoju Road, Shanghai, China.
Chi ChenInstitute and department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No.639 Zhizaoju Road, Shanghai, China.
Bing HanInstitute and department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No.639 Zhizaoju Road, Shanghai, China. foxhb1423@126.com.
Yingli LuInstitute and department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, No.639 Zhizaoju Road, Shanghai, China. luyingli2008@126.com.ORCID http://orcid.org/0000-0002-5117-1614
Shanghai Ninth People's Hospital · CN

Funding

Commission of Health and Family Planning of Pudong District PWZxq2017-17Municipal Human Resources Development Program for Outstanding Young Talents in Medical and Health Sciences in Shanghai 2017YQ053National Natural Science Foundation of China 91857117, 81670717School of Medicine, University of Kansas 19XJ11007Science and Technology Commission of Shanghai Municipality 19140902400, 18410722300the Major Science and Technology Innovation Program of Shanghai Municipal Education Commission 2019-01-07-00-01-E00059
6 · The paper itself

Abstract

backgroundUric acid (UA) is the end product of purine metabolism, which is thought to be related to many human diseases, such as nephrolithiasis, gout, cardiovascular disease (CVD), type 2 diabetes mellitus, metabolic syndrome. However, the relationship between serum UA (SUA) and 25(OH) D is still unclear in the eastern Chinese population.

methodsWe did a population-based observational investigation, which included 12,770 residents living in eastern China. Ultimately, data from 9220 subjects were analyzed. Serum 25(OH) D, SUA, fasting plasma glucose (FPG), fasting insulin, HbA1c and other metabolic parameters were tested. Waist circumference (WC), weight and height were also measured. Questionnaires were collected from these subjects for information on smoking and drinking status.

resultsWe enrolled 9220 Chinese adults, including 3681 males (age 55.57 ± 13.23 years) and 5539 females (age 54.31 ± 12.83 years). The levels of SUA were 352.07 ± 79.25 nmol/L and 269.29 ± 64.68 nmol/L in males and females, respectively. The proportion of adults with hyperuricemia (HUA) was 12.26% in the total population. Levels of SUA were positively associated with 25(OH) D, and the incidence of HUA increased 9.4% for every 10 nmol/L increase in 25(OH) D (P < 0.001).

conclusionsSUA was positively associated with 25(OH) D in the eastern Chinese population. Higher levels of serum 25(OH) D may be a potential predictor of HUA.

Indexed as

AdultAgedBlood GlucoseBody Mass IndexCase-Control StudiesChinaFemaleGlycated HemoglobinHumansHyperuricemiaInsulinLinear ModelsLogistic ModelsMaleMiddle AgedUric Acid25-hydroxyvitamin DBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanInsulinUric AcidVitamin DHyperuricemiaPublic healthUric acidVitamin D

Identifiers

PMID32493273
PMCPMC7268462
OpenAlexW3032235427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.