ArticleBMC pediatrics2020
Prevalence of congenital malformations at the "les Orangers" maternity and reproductive health Hospital of Rabat: descriptive study of 470 anomalies.
Article in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Diagnostic accuracy of ultrasound screening for fetal structural abnormalities during the first and second trimester of pregnancy in low-risk and unselected populations.The Cochrane database of systematic reviews · 2024Pooled it
- Global prevalence of congenital anencephaly: a comprehensive systematic review and meta-analysis.Reproductive health · 2022Pooled it
- Proportion of Chromosomal Disorders and Their Patterns among Births with Congenital Anomalies in Africa: A Systematic Review and Meta-Analyses.TheScientificWorldJournal · 2022Pooled it
- Congenital Anomaly Prevalence: A 10-Year Retrospective Study in a Tertiary Hospital in Turkey.Birth defects research · 2026Article
- Determinants of congenital anomalies among newborns in public hospitals of Northern Ethiopia: case-control study design.Scientific reports · 2026Article
- Association of preterm birth and congenital anomalies: findings of a Brazilian multicenter study.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026Observational
- Global, regional, and national burden of congenital musculoskeletal and limb anomalies, 1990-2021: a systematic analysis of the global burden of disease in 2021.Tropical medicine and health · 2025Article
- Epidemiology of congenital anomalies in the Gulf Cooperation Council countries: a scoping review.BMJ open · 2025Article
- Are congenital malformations associated with maternal sociodemographic and risk factors? A multicenter ultrasound-based study.Pakistan journal of medical sciences · 2024Article
- Congenital Malformations in the Moroccan Surveillance System: Contribution to Prevalence Estimation.Global health, epidemiology and genomics · 2024Article
- High glucose causes developmental abnormalities in neuroepithelial cysts with actin and HK1 distribution changes.Frontiers in cell and developmental biology · 2022Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCongenital malformations are described in about 3% of live births and 20% of stillbirths in the industrialized countries. The prevalence of congenital anomalies in developing countries, including Morocco, is not well known at the national level. The aim of our study is to conduct a descriptive exploratory analysis of congenital malformations cases diagnosed at the "Les Orangers" Maternity and Reproductive Health Hospital in Rabat.
methodsWe collected all the cases of congenital malformations diagnosed at the "Les Orangers" Maternity and Reproductive Health Hospital in Rabat, from January 1st, 2011 to June 31st, 2016. Data were reported on pre-established sheets and on a registry of malformations. Total and specific prevalences were calculated for each malformation. A principal component analysis (PCA) was then conducted followed by a Varimax rotation in order to identify the different associations of malformations in our series.
resultsWe registred 245 cases of congenital malformations out of a total of 43,923 recorded births; a prevalence of 5.58 per thousand births of which 19.2% were FDIU (fetal deaths in utero). A polymalformative syndrome was found in 26.5% of cases which makes a total number of 470 anomalies. The musculoskeletal anomalies predominate with a rate of 33%, followed by neurological abnormalities 18%, of whom 31% were hydrocephalus, 26.2% anencephaly, and 20.24% spina bifida. Malformations of the eye, ear, face and neck were described in 12% of the cases, while genetic abnormalities were observed in 8,5% of which 87.5% represented Down syndrome. The antenatal diagnosis of congenital malformations was performed in 28.6% of cases.
conclusionsOur study provides a general overview of the epidemiological situation related to different types of congenital anomalies for a specific area in Morocco. It represents a database that should be complemented by other multicenter studies and the implementation of a national registry to determine the prevalence of congenital malformations at a national level.
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