Evidence map›Paper›PMID 32493036›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2020

Effects of electroacupuncture on stress-induced gastric dysrhythmia and mechanisms involving autonomic and central nervous systems in functional dyspepsia.

Sujuan Zhang, Yi Liu, Shiying Li, Feng Ye, Robert D Foreman, Jiande D Z Chen

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Sujuan ZhangVeterans Research and Education Foundation, Veterans Affairs Medical Center, Oklahoma City, Oklahoma.
Yi LiuVeterans Research and Education Foundation, Veterans Affairs Medical Center, Oklahoma City, Oklahoma.
Shiying LiVeterans Research and Education Foundation, Veterans Affairs Medical Center, Oklahoma City, Oklahoma.
Feng YeVeterans Research and Education Foundation, Veterans Affairs Medical Center, Oklahoma City, Oklahoma.
Robert D ForemanDepartment of Physiology, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma.
Jiande D Z ChenVeterans Research and Education Foundation, Veterans Affairs Medical Center, Oklahoma City, Oklahoma.
Johns Hopkins University · USUniversity of Oklahoma Health Sciences Center · USFirst Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CN

Funding

University of Michigan Center for Gastrointestinal ResearchP30DK034933 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OMARY, BISHR · 1986 to 2021
$22.5M
NIDDK NIH HHS P30 DK034933
6 · The paper itself

Abstract

Electroacupuncture (EA) is widely used as an effective method to treat stress-related disorders. However, its mechanisms remain largely unknown. The aim of this study was to investigate the effects and mechanisms of EA on gastric slow wave (GSW) dysrhythmia and c-Fos expression in the nucleus of the solitary tract (NTS) induced by stress in a rodent model of functional dyspepsia (FD). Rats in the neonatal stage were treated using intragastric iodoacetamide. Eight weeks later, the rats were implanted with electrodes in the stomach for the measurement of GSW and electrodes into accupoints ST36 for EA. Autonomic functions were assessed by spectral analysis of heart rate variability. Rats were placed for 30 min in a cylindrical plastic tube for acute restraint stress. The involvement of a central afferent pathway was assessed by measuring c-Fos-immunoreactive cells in the NTS.

Indexed as

ElectroacupunctureAfferent PathwaysAnimalsAnimals, NewbornAutonomic Nervous SystemCentral Nervous SystemDyspepsiaGastric EmptyingIodoacetamideMaleNorepinephrineProto-Oncogene Proteins c-fosRatsRats, Sprague-DawleyRestraint, PhysicalSolitary NucleusIodoacetamideNorepinephrineProto-Oncogene Proteins c-foscentral and autonomic pathwayselectroacupuncturefunctional dyspepsiagastric slow wavesstress

Identifiers

PMID32493036
PMCPMC8424570
OpenAlexW3032215251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.