Evidence map›Paper›PMID 32492956›Full record

ArticleMolecules (Basel, Switzerland)2020

New Morphiceptin Peptidomimetic Incorporating (1

Raquel Soengas, Marcos Lorca, Begoña Pampín, Víctor M Sánchez-Pedregal, Ramón J Estévez, Juan C Estévez

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raquel SoengasDepartmento de Química Orgánica e Inorgánica, Universidad de Oviedo, Julián Clavería 8, 33006 Oviedo, Spain.ORCID 0000-0001-8178-0034
Marcos LorcaCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Begoña PampínDepartamento de Química Orgánica, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Víctor M Sánchez-PedregalDepartamento de Química Orgánica, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0003-1581-0455
Ramón J EstévezCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-3764-0832
Juan C EstévezCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.

Funding

Conicyt PFCHA/Doctorado Nacional/2018-21180427European Regional Development Fund ERDFPrincipado de Asturias FICYT IDI/2018/000181Spanish Ministry of Science and Innovation CTQ2009-08490Xunta de Galicia Centro Singular de Investigación de Galicia, Centro singular de investigación de Galicia accreditation 2019-2022, ED431G 2019/03; Project CN2011/037, project ED431C 2018/04 and Project GRC2014/040
6 · The paper itself

Abstract

We present the synthesis and structural study of a new peptidomimetic of morphiceptin, which can formally be considered as the result of the replacement of the central proline residue of this natural analgesic drug with a subunit of (1

Indexed as

AlgorithmsAnalgesicsBinding SitesCarboxylic AcidsChemistry, PharmaceuticalChemistry Techniques, SyntheticComputer SimulationDrug DesignEndorphinsLigandsMagnetic Resonance SpectroscopyMolecular Docking SimulationPeptidesPeptidomimeticsProlineSugarsAnalgesicsCarboxylic AcidsEndorphinsLigandsmorphiceptinPeptidesPeptidomimeticsProlineSugarsalicyclic β-amino acidsanalgesicmorphiceptinnitro sugarspeptidomimetics

Identifiers

PMID32492956
PMCPMC7321350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.