Evidence map›Paper›PMID 32492783›Full record

ArticleJournal of clinical medicine2020

Conversion from Standard-Release Tacrolimus to MeltDose

Johannes von Einsiedel, Gerold Thölking, Christian Wilms, Elena Vorona, Arne Bokemeyer, Hartmut H Schmidt, Iyad Kabar, Anna Hüsing-Kabar

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Early Conversion to Once-Daily MeltDoseJournal of clinical medicine · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Tacrolimus-why pharmacokinetics matter in the clinic.Frontiers in transplantation · 2023
    Review
  10. Article
  11. Article
  12. Commentary: The Clinical Impact of the CFrontiers in pharmacology · 2021
    Article
  13. Real-World Administration of Once-Daily MeltDoseJournal of clinical medicine · 2020
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Johannes von EinsiedelDepartment of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, 48149 Münster, Germany.
Gerold ThölkingDepartment of Internal Medicine and Nephrology, University Hospital of Münster Marienhospital Steinfurt, 48565 Steinfurt, Germany.ORCID 0000-0003-3180-6245
Christian WilmsDepartment of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, 48149 Münster, Germany.
Elena VoronaDepartment of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, 48149 Münster, Germany.
Arne BokemeyerDepartment of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, 48149 Münster, Germany.
Hartmut H SchmidtDepartment of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, 48149 Münster, Germany.
Iyad KabarDepartment of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, 48149 Münster, Germany.
Anna Hüsing-KabarDepartment of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, 48149 Münster, Germany.
University Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal impairment is a typical side effect of tacrolimus (Tac) treatment in liver transplant (LT) recipients. One strategy to avoid renal dysfunction is to increase the concentration/dose (C/D) ratio by improving drug bioavailability. LT recipients converted from standard-release Tac to MeltDose

Indexed as

C/D ratioLCPTliver transplantationMeltDose®metabolismrenal functiontacrolimus

Identifiers

PMID32492783
PMCPMC7356524
OpenAlexW3030698284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.