Evidence map›Paper›PMID 32492411›Full record

ArticleStructure (London, England : 1993)2020

Cobbling Together the Myddosome.

Michelle L D Snyder, Greg A Snyder

Abstract readComment
PubMed Publisher
In one paragraph

Article in Structure (London, England : 1993), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The theory of the inflammatory ecosystem.Science China. Life sciences · 2026
    Review
  2. Hangeshashinto InhibitsEvidence-based complementary and alternative medicine : eCAM · 2024
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michelle L D SnyderTowson University, Department of Biological Sciences, 8000 York Rd., Towson, MD 21212, USA.
Greg A SnyderInstitute of Human Virology, University of Maryland School of Medicine, 725 West Lombard Street, Baltimore, MD 21201, USA. Electronic address: gsnyder@som.umaryland.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An organism's ability to recognize and respond quickly and appropriately to pathogenic stimuli is a fundamental aspect of innate immunity. Harnessing the dynamic nature of fluorescent microscopy and the resolution of cryo-electron microscopy, Moncrieffe et al. (2020) characterize MyD88-only filaments and provide insight into the mechanisms underlying innate immune signaling.

Indexed as

Myeloid Differentiation Factor 88Toll-Like ReceptorsAdaptor Proteins, Signal TransducingCryoelectron MicroscopyImmunity, InnateSignal TransductionAdaptor Proteins, Signal TransducingMyeloid Differentiation Factor 88Toll-Like Receptors

Identifiers

PMID32492411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.