ArticlePloS one2020
Systemic factors associated with intraocular pressure among subjects in a health examination program in Japan.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
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- Risk factors associated with elevated intraocular pressure: a population-based study in a rural community of Bangladesh.BMJ open ophthalmology · 2023Article
- Linear association between aging and decreased blood thiol antioxidant activity in patients with cataract.Journal of clinical biochemistry and nutrition · 2023Article
- Age-specific distribution of intraocular pressure in elderly Iranian population and its associated factors.Caspian journal of internal medicine · 2023Article
- Distribution and associated factors of intraocular pressure in the older population: Tehran Geriatric Eye Study.International journal of ophthalmology · 2023Article
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- The Association Between Age and Systemic Variables and the Longitudinal Trend of Intraocular Pressure in a Large-Scale Health Examination Cohort.Investigative ophthalmology & visual science · 2022Article
- The Impact of Systemic Health Parameters on Intraocular Pressure in the Western Region of Saudi Arabia.Cureus · 2022Article
- Comparisons of optic nerve head morphology parameters between the presence and absence of silent brain infarctions.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- The effect of daily life activities on intraocular pressure related variations in open-angle glaucoma.Scientific reports · 2021Article
- Predicting intraocular pressure using systemic variables or fundus photography with deep learning in a health examination cohort.Scientific reports · 2021Article
- Prevalence of Epiretinal Membrane among Subjects in a Health Examination Program in Japan.Life (Basel, Switzerland) · 2021Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo elucidate the possible effect of various systemic factors on intraocular pressure (IOP) using a dataset from a health examination program database in Japan.
methodsThis cross-sectional study included 1569 subjects selected from the 2287 subjects who comprised the database. Various systemic parameters including age, sex, height, body weight, waist circumference, percent body fat, blood pressure (BP), pulse rate, body mass index, 28 blood examination values, intimal medial thicknesses of both carotid arteries, and intraocular pressure (IOP) values measured by non-contact tonometry in both eyes were collected. The possible correlation between the IOP and other parameters was assessed initially by univariate analyses followed by multivariate analyses.
resultsStepwise multivariate analyses, which included all parameters extracted by the univariate analyses (p<0.1) and sex, identified the same six parameters as indicators of the IOP values for each right and left IOP model. Among the parameters, age (r = -0.05 and -0.04/year for right and left IOPs, respectively) was associated negatively and the percent body fat (r = 0.06 and 0.05/%), systolic BP (r = 0.02 and 0.03/mmHg), pulse rate (r = 0.03 and 0.03/counts/minutes), albumin (r = 1.12 and 1.00/g/dL), and hemoglobin A1c (r = 0.38 and 0.44/%) were associated positively with the IOP in each eye.
conclusionsOlder age was associated with low IOP, while factors reflecting the metabolic syndrome were associated with high IOP in our study population.
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