Evidence map›Paper›PMID 32491888›Full record

ArticleChaos (Woodbury, N.Y.)2020

Asymptotic estimates of SARS-CoV-2 infection counts and their sensitivity to stochastic perturbation.

Davide Faranda, Isaac Pérez Castillo, Oliver Hulme, Aglaé Jezequel, Jeroen S W Lamb, Yuzuru Sato, Erica L Thompson

Abstract read
In one paragraph

Article in Chaos (Woodbury, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Understanding the Challenges and Uncertainties of Seroprevalence Studies for SARS-CoV-2.International journal of environmental research and public health · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. A stretched logistic equation for pandemic spreading.Chaos, solitons, and fractals · 2020
    Article
  13. Article
  14. Long-term forecasts of the COVID-19 epidemic: a dangerous idea.Revista da Sociedade Brasileira de Medicina Tropical · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Davide FarandaLaboratoire des Sciences du Climat et de l'Environnement, CEA Saclay l'Orme des Merisiers, UMR 8212 CEA-CNRS-UVSQ, Université Paris-Saclay and IPSL, 91191 Gif-sur-Yvette, France.ORCID 0000000150015698
Isaac Pérez CastilloLondon Mathematical Laboratory, 8 Margravine Gardens, London W6 8RH, United Kingdom.
Oliver HulmeLondon Mathematical Laboratory, 8 Margravine Gardens, London W6 8RH, United Kingdom.
Aglaé JezequelLMD/IPSL, ENS, PSL Université, École Polytechnique, Institut Polytechnique de Paris, Sorbonne Université, CNRS, 75005 Paris, France.
Jeroen S W LambLondon Mathematical Laboratory, 8 Margravine Gardens, London W6 8RH, United Kingdom.
Yuzuru SatoLondon Mathematical Laboratory, 8 Margravine Gardens, London W6 8RH, United Kingdom.ORCID 0000000267532218
Erica L ThompsonLondon Mathematical Laboratory, 8 Margravine Gardens, London W6 8RH, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the importance of having robust estimates of the time-asymptotic total number of infections, early estimates of COVID-19 show enormous fluctuations. Using COVID-19 data from different countries, we show that predictions are extremely sensitive to the reporting protocol and crucially depend on the last available data point before the maximum number of daily infections is reached. We propose a physical explanation for this sensitivity, using a susceptible-exposed-infected-recovered model, where the parameters are stochastically perturbed to simulate the difficulty in detecting patients, different confinement measures taken by different countries, as well as changes in the virus characteristics. Our results suggest that there are physical and statistical reasons to assign low confidence to statistical and dynamical fits, despite their apparently good statistical scores. These considerations are general and can be applied to other epidemics.

Indexed as

Stochastic ProcessesAsymptomatic InfectionsBetacoronavirusChinaCoronavirus InfectionsCOVID-19Global HealthHumansModels, StatisticalNonlinear DynamicsPandemicsPneumonia, ViralSARS-CoV-2

Identifiers

PMID32491888
PMCPMC7241685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.