Evidence map›Paper›PMID 32491278›Full record

ReviewCNS neuroscience & therapeutics2020

Exercise, brain plasticity, and depression.

Jin-Lei Zhao, Wan-Ting Jiang, Xing Wang, Zhi-Dong Cai, Zu-Hong Liu, Guo-Rong Liu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in CNS neuroscience & therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 18 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 18 syntheses or guidelines pooled it, 216 citations in OpenAlex.

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59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jin-Lei ZhaoSchool of Physical Education and Health, Shanghai Lixin University of Accounting and Finance, Shanghai, China.
Wan-Ting JiangDepartment of Physical Education and Sport Training, Shanghai University of Sport, Shanghai, China.ORCID 0000-0001-5484-6173
Xing WangDepartment of Physical Education and Sport Training, Shanghai University of Sport, Shanghai, China.
Zhi-Dong CaiDepartment of Physical Education and Sport Training, Shanghai University of Sport, Shanghai, China.
Zu-Hong LiuDepartment of Physical Education and Sport Training, Shanghai University of Sport, Shanghai, China.
Guo-Rong LiuSchool of Physical Education and Health, Shanghai Lixin University of Accounting and Finance, Shanghai, China.
Shanghai University of Sport · CNShanghai Lixin University of Accounting and Finance · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a common mental disorder characterized by high incidence, high disability, and high fatality, causing great burden to the society, families, and individuals. The changes in brain plasticity may be a main reason for depression. Recent studies have shown that exercise plays a positive role in depression, but systematic and comprehensive studies are lacking on brain plasticity changes in depression. To further understand the antidepressive effect of exercise and the changes in brain plasticity, we retrieved related literatures using key words "depression," "depressive disorder," "exercise," "brain plasticity," "brain structure," and "brain function" from the database of Web of Science, PubMed, EBSCO host, and CNKI, hoping to provide evidence for exercise in preventing and treating depression. Increase in exercise has been found negatively correlated with the risk of depression. Randomized controlled experiments have shown that aerobic exercise, resistance exercise, and mind-body exercise can improve depressive symptoms and levels. The intensity and long-term effect of exercise are now topical research issues. Exercise has been proven to reshape the brain structure of depression patients, activate the function of related brain areas, promote behavioral adaptation changes, and maintain the integrity of hippocampal and white matter volume, thus improving the brain neuroprocessing and delaying cognitive degradation in depression patients. Future studies are urgently needed to establish accurate exercise prescriptions for improving depressive symptoms, and studies on different depressive populations and studies using multimodal brain imaging combined with multiple analytical methods are also needed.

Indexed as

Adaptation, PsychologicalBrainDepressionExerciseHumansNeuronal Plasticitybrain functionbrain plasticitybrain structuredepressionexercise

Identifiers

PMID32491278
PMCPMC7415205
OpenAlexW3030952704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.