Evidence map›Paper›PMID 32490966›Full record

SynthesisArquivos de neuro-psiquiatria2020

Neurological complications in patients with SARS-CoV-2 infection: a systematic review.

Renato Puppi Munhoz, José Luiz Pedroso, Fábio Augusto Nascimento, Sergio Monteiro de Almeida, Orlando Graziani Povoas Barsottini, Francisco Eduardo C Cardoso, Hélio A Ghizoni Teive

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Arquivos de neuro-psiquiatria, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. A Comprehensive Systematic Review of CSF analysis that defines Neurological Manifestations of COVID-19.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Observational
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Effects of COVID-19 on children with autism.World journal of virology · 2022
    Review
  15. Article
  16. Olfactory Dysfunction is Associated with More Severe Clinical Course in COVID-19.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  17. Review
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Renato Puppi MunhozMovement Disorders Centre, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-4783-4067
José Luiz PedrosoDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-1672-8894
Fábio Augusto NascimentoDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-7161-6385
Sergio Monteiro de AlmeidaNeuroinfection Outclinic, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.ORCID 0000-0001-5690-105X
Orlando Graziani Povoas BarsottiniDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0002-0107-0831
Francisco Eduardo C CardosoMovement Disorders Unit, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID 0000-0003-0808-0116
Hélio A Ghizoni TeiveInternal Medicine Department, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.ORCID 0000-0003-2305-1073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the COVID-19 pandemic unfolds worldwide, different forms of reports have described its neurologic manifestations.

objectiveTo review the literature on neurological complications of SARS-CoV-2 infection.

methodsLiterature search performed following systematic reviews guidelines, using specific keywords based on the COVID-19 neurological complications described up to May 10th, 2020.

resultsA total of 43 articles were selected, including data ranging from common, non-specific symptoms, such as hyposmia and myalgia, to more complex and life-threatening conditions, such as cerebrovascular diseases, encephalopathies, and Guillain-Barré syndrome.

conclusionRecognition of neurological manifestations of SARS-CoV-2 should be emphasized despite the obvious challenges faced by clinicians caring for critical patients who are often sedated and presenting other concurrent systemic complications.

Indexed as

AgeusiaBrain DiseasesCerebrovascular DisordersCoronavirus InfectionsCOVID-19Guillain-Barre SyndromeHumansMyalgiaNervous System DiseasesOlfaction DisordersPandemicsPneumonia, Viral

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.