Evidence map›Paper›PMID 32490813›Full record

ArticleeLife2020

Synaptotagmin-1 is the Ca

Aditi Banerjee, Jinoh Lee, Paulina Nemcova, Changliang Liu, Pascal S Kaeser

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. The Synaptic Vesicle Priming Protein Munc13 Mediates Evoked Somatodendritic Dopamine Release.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Aditi BanerjeeDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID 0000-0003-2016-0717
Jinoh LeeDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID 0000-0002-2158-8507
Paulina NemcovaDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID 0000-0002-0323-8079
Changliang LiuDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Pascal S KaeserDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID 0000-0002-1558-1958
Harvard University · US

Funding

Super-Resolution ImagingP30NS072030 · NINDS · HARVARD MEDICAL SCHOOL · PI REGEHR, WADE G · 2011 to 2020
$5.8M
Architecture and Function of Striatal Dopamine Signaling MachineryR01NS103484 · NINDS · HARVARD MEDICAL SCHOOL · PI Pascal Simon Kaeser · 2017 to 2026
$4.7M
NINDS NIH HHS P30 NS072030NINDS NIH HHS R01 NS103484NINDS NIH HHS R01NS103484
6 · The paper itself

Abstract

Dopamine powerfully controls neural circuits through neuromodulation. In the vertebrate striatum, dopamine adjusts cellular functions to regulate behaviors across broad time scales, but how the dopamine secretory system is built to support fast and slow neuromodulation is not known. Here, we set out to identify Ca

Indexed as

AnimalsCalciumCorpus StriatumDopamineFemaleMaleMiceMice, KnockoutNeuronsSynapsesSynaptotagmin ICalciumDopamineSynaptotagmin ISyt1 protein, mousecalcium sensorcell biologydopaminemouseneuromodulationneurosciencesecretionstriatum

Identifiers

PMID32490813
PMCPMC7319770
OpenAlexW3030445897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.