Evidence map›Paper›PMID 32490377›Full record

ArticleProceedings of machine learning research2019

Phenotype Inference with Semi-Supervised Mixed Membership Models.

Victor A Rodriguez, Adler Perotte

Abstract read
In one paragraph

Article in Proceedings of machine learning research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Probabilistic Machine Learning for Healthcare.Annual review of biomedical data science · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Victor A RodriguezColumbia University, Department of Biomedical Informatics, New York City, NY, USA.
Adler PerotteColumbia University, Department of Biomedical Informatics, New York City, NY, USA.

Funding

Probabilistic modeling of observational clinical data for high-throughput inference of disease phenotypesF31LM012894 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RODRIGUEZ, VICTOR ALFONSO · 2018 to 2022
$253k
NLM NIH HHS F31 LM012894
6 · The paper itself

Abstract

Disease phenotyping algorithms are designed to sift through clinical data stores to identify patients with specific diseases. Supervised phenotyping methods require significant quantities of expert-labeled data, while unsupervised methods may learn spurious or non-disease phenotypes. To address these limitations, we propose the Semi-Supervised Mixed Membership Model (SS3M) - a probabilistic graphical model for learning disease phenotypes from partially labeled clinical data. We show SS3M can generate interpretable, disease-specific phenotypes which capture the clinical features of the disease concepts specified by the labels provided to the model. Furthermore, SS3M phenotypes demonstrate competitive predictive performance relative to commonly used baselines.

Identifiers

PMID32490377
PMCPMC7266114

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.