Evidence map›Paper›PMID 32490301›Full record

ArticleGeoHealth2020

Elevated Hair Mercury Levels Are Associated With Neurodevelopmental Deficits in Children Living Near Artisanal and Small-Scale Gold Mining in Peru.

Aaron Reuben, Helena Frischtak, Axel Berky, Ernesto J Ortiz, Ana Maria Morales, Heileen Hsu-Kim, Laura L Pendergast, William K Pan

Open access · goldAbstract read
In one paragraph

Article in GeoHealth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Mercury Levels in Hair of Pregnant Women in Tumbes, Peru: A Cross-Sectional Study.The American journal of tropical medicine and hygiene · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Environmental health perspectives · 2023
    Article
  10. Levels of Toxic and Essential Elements and Associated Factors in the Hair of Japanese Young Children.International journal of environmental research and public health · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Aaron ReubenDepartment of Psychology and Neuroscience Duke University Durham NC USA.ORCID https://orcid.org/0000-0001-5713-4913
Helena FrischtakContra Costa Regional Medical Center Martinez CA USA.
Axel BerkyGlobal Health Institute Duke University Durham NC USA.
Ernesto J OrtizGlobal Health Institute Duke University Durham NC USA.ORCID https://orcid.org/0000-0002-6485-2005
Ana Maria MoralesCentro de Estudios, Investigaciones y Servicios en Salud Publica (CENSAP) Puerto Maldonado Peru.
Heileen Hsu-KimNicholas School of the Environment Duke University Durham NC USA.ORCID https://orcid.org/0000-0003-0675-4308
Laura L PendergastDepartment of Psychological Studies in Education Temple University Philadelphia PA USA.
William K PanGlobal Health Institute Duke University Durham NC USA.ORCID https://orcid.org/0000-0002-7407-7399
Duke University · USCentro Peruano de Estudios Sociales · PEContra Costa Regional Medical Center · USTemple University · US

Funding

Science CoreP2CHD065563 · NICHD · DUKE UNIVERSITY · PI James Moody · 2015 to 2026
$5.7M
Impact of El Nino on Environmental Mercury and Human ExposureR21ES026960 · NIEHS · DUKE UNIVERSITY · PI PAN, WILLIAM KUANG-YAO · 2016 to 2017
$343k
Evaluating neurodegenerative risk in middle-aged adults exposed to lead as childrenF31ES029358 · NIEHS · DUKE UNIVERSITY · PI REUBEN, AARON · 2018 to 2020
$113k
NICHD NIH HHS P2C HD065563NIEHS NIH HHS F31 ES029358NIEHS NIH HHS R21 ES026960
6 · The paper itself

Abstract

Children living near artisanal and small-scale gold mining (ASGM) are at risk of exposure to mercury, a neurotoxicant. It is not certain whether such exposures are harming development, as they occur in underresourced contexts entwined with other stressors, such as malnutrition and enteric infection. This study sought to investigate the association between hair-mercury levels and visual-motor, cognitive, and physical development among children living near ASGM in the Peruvian Amazon. Total hair-mercury levels were measured in 164 children ages 5-12 living in Madre de Dios, Peru. Primary outcomes included Visual-Motor Integration assessed via the Beery-VMI Developmental Test, General Cognitive Ability assessed via the Batería-III Woodcock-Munoz (Spanish-language Woodcock-Johnson Tests of Cognitive Abilities), and Physical Health assessed via anthropometry/hemoglobin counts. Mean (SD) hair-mercury level was 2.06 (2.43) μg/g. Fifty-four children (32.9%) had hair-mercury levels above the World Health Organization reference level of 2.0 μg/g. After controlling for sex, child age, maternal education, and family socioeconomic status, each one unit increase in log hair-mercury level was associated with a 1.01 unit decrease in Visual-Motor Integration (95%CI: -2.06, 0.05,

Indexed as

artisanal and small‐scale gold miningchild developmentenvironmental pollutionmercuryneurocognitive assessment

Identifiers

PMID32490301
PMCPMC7240868
OpenAlexW3026561740

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.