ArticleHeliyon2020
Changes in some haematological parameters in typhoid fever patients attending Landmark University Medical Center, Omuaran-Nigeria.
Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Physical Signs and Hematological and Biochemical Alterations in Salmonella-Plasmodium Sequentially Coinfected Albino Wistar Rats.TheScientificWorldJournal · 2026Article
- Whole-Genome Sequencing Analysis of Drug-ResistantPathogens (Basel, Switzerland) · 2025Article
- Clinical characteristics and prognosis of non-typhoidalFrontiers in medicine · 2025Article
- Stress-mediating inflammatory cytokine profiling reveals unique patterns in malaria and typhoid fever patients.PloS one · 2025Observational
- Article
- PCT, IL-6, and IL-10 facilitate early diagnosis and pathogen classifications in bloodstream infection.Annals of clinical microbiology and antimicrobials · 2023Article
- Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTyphoid or enteric fever is caused by
objectivesThis study was carried out to determine the changes in various hematological parameters in our study subjects.
methodFour Hundred- (400) samples were obtained from volunteer subjects visiting the outpatient department of the Landmark University Medical Center. 200 typhoid positive samples were collected from subjects while 200 typhoid negative blood samples served as controls (From both male and female subjects each). Widal test was carried out as a confirmatory test for typhoid fever and evaluation of the hematological parameters were performed. The hematological parameters considered includes Packed Cell Volume (PCV), White Blood Cell count (WBC), Platelet count (PLT), Lymphocyte (LYMP) their implications on both male and female typhoid fever patients were also determined.
resultsThe result showed a significant reduction in the values for PCV, WBC, ESR and HAE concentration in typhoid positive males in comparison to typhoid negative males. In females, a significant decrease was observed in values for PCV, ESR, HAE concentration and PLT in typhoid positive females when compared to typhoid negative females. These parameters when compared showed a significant decrease recorded in PCV, ESR and HAE concentration of the typhoid positive male patients in comparison to typhoid positive female patients.
conclusionThis study implies that anemia, bone marrow suppression and hemaphagocytosis are likely resulting factors of typhoid fever due to the changes in the hematological parameters. Therefore, these parameters have to be further studied to allow for efficient management of this illness.
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