Evidence map›Paper›PMID 32489782›Full record

Observational studyGlobal heart2020

Patterns of Emergency Care for Possible Acute Coronary Syndrome Among Patients with Chest Pain or Shortness of Breath at a Tanzanian Referral Hospital.

Julian T Hertz, Godfrey L Kweka, Gerald S Bloomfield, Alexander T Limkakeng, Zak Loring, Gloria Temu, Blandina T Mmbaga, Charles J Gerardo, Francis M Sakita

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Global heart, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  5. Acute coronary syndrome prevalence and outcomes in a Tanzanian emergency department: Results from a prospective surveillance study.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025
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  9. Evaluating the performance of the HEART score in a Tanzanian emergency department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2024
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Julian T HertzDivision of Emergency Medicine, Duke University School of Medicine, Durham, NC, US.
Godfrey L KwekaKilimanjaro Clinical Research Institute, Moshi, TZ.
Gerald S BloomfieldDuke Global Health Institute, US.
Alexander T LimkakengDivision of Emergency Medicine, Duke University School of Medicine, Durham, NC, US.
Zak LoringDivision of Cardiology, Duke University School of Medicine, NC, US.
Gloria TemuDepartment of Medicine, Kilimanjaro Christian Medical Centre, Moshi, TZ.
Blandina T MmbagaKilimanjaro Clinical Research Institute, Moshi, TZ.
Charles J GerardoDivision of Emergency Medicine, Duke University School of Medicine, Durham, NC, US.
Francis M SakitaDepartment of Emergency Medicine, Kilimanjaro Christian Medical Centre, Moshi, TZ.
Duke University · USClinical Research Institute · USKilimanjaro Christian Medical Centre · TZ

Funding

Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
FIC NIH HHS D43 TW009337
6 · The paper itself

Abstract

Background: Acute coronary syndrome (ACS) is thought to be a rare diagnosis in sub-Saharan Africa, but little is known about diagnostic practices for patients with possible ACS symptoms in the region. Objective: To describe current care practices for patients with ACS symptoms in Tanzania to identify factors that may contribute to ACS under-detection. Methods: Emergency department patients with chest pain or shortness of breath at a Tanzanian referral hospital were prospectively observed. Medical histories were obtained, and diagnostic workups, treatments, and diagnoses were recorded. Five-year risk of cardiovascular events was calculated via the Harvard National Health and Nutrition Examination Survey risk score. Telephone follow-ups were conducted 30 days after enrollment. Results: Of 339 enrolled patients, the median (IQR) age was 60 (46, 72) years, 252 (74.3%) had hypertension, and 222 (65.5%) had >10% five-year risk of cardiovascular event. The median duration of symptoms prior to presentation was 7 days, and 314 (92.6%) reported symptoms worsened by exertion. Of participants, 170 (50.1%) received an electrocardiogram, and 9 (2.7%) underwent cardiac biomarker testing. There was no univariate association between five-year cardiovascular risk and decision to obtain an electrocardiogram ( Conclusions: Many patients with ACS risk factors present to the emergency department of a Tanzanian referral hospital with possible ACS symptoms, but marked delays in care-seeking are common. Complete diagnostic workups for ACS are uncommon, ACS is rarely diagnosed or treated with evidence-based therapies, and mortality in patients with these symptoms is high. Physician practices may be contributing to ACS under-detection in Tanzania, and interventions are needed to improve ACS care.

Indexed as

Disease ManagementRisk AssessmentAcute Coronary SyndromeAgedChest PainDyspneaElectrocardiographyEmergency Medical ServicesFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedProspective StudiesReferral and Consultationacute coronary syndromeemergency departmentsub-Saharan AfricaTanzania

Identifiers

PMID32489782
PMCPMC7218785
OpenAlexW3010023969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.