Evidence map›Paper›PMID 32489774›Full record

ReviewGlobal heart2020

Periodontitis and Cardiovascular Diseases. Consensus Report.

M Sanz, A Marco Del Castillo, S Jepsen, J R Gonzalez-Juanatey, F D'Aiuto, P Bouchard, I Chapple, T Dietrich, I Gotsman, F Graziani and 11 more

Open access · goldAbstract readReviewConsensus Statement
In one paragraph

Review in Global heart, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 7 pooled it
24.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 7 syntheses or guidelines pooled it, 261 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Observational
  20. Article

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 19 institutions in 12 countries.

M SanzDepartment of Dental Clinical Specialties and ETEP Research Group, Faculty of Odontology, University Complutense of Madrid, Plaza Ramon y Cajal, Madrid, ES.
A Marco Del CastilloCardiology Department, Hospital Universitario Ramon y Cajal, Madrid, ES.
S JepsenDepartment of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, DE.
J R Gonzalez-JuanateyCardiology Department, University Hospital, University of Santiago de Compostela, IDIS, CIBERCV, ES.
F D'AiutoDepartment of Periodontology, Eastman Dental Institute and Hospital, University College London, London, UK.
P BouchardU.F.R. d'odontologie, Université Paris Diderot, Hôpital Rothschild AP-HP, Paris, FR.
I ChappleSchool of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, The University of Birmingham, Birmingham, UK.
T DietrichSchool of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, The University of Birmingham, Birmingham, UK.
I GotsmanHeart Institute, Hadassah University Hospital, Jerusalem, IL.
F GrazianiDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, IT.
D HerreraDepartment of Dental Clinical Specialties and ETEP Research Group, Faculty of Odontology, University Complutense of Madrid, Plaza Ramon y Cajal, Madrid, ES.
B LoosACTA University, Amsterdam, NL.
P MadianosDepartment of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, GR.
J B MichelInserm Unit 1148, laboratory for translational CV science, X. Bichat hospital, Paris, FR.
P PerelWorld Heart Federation, Geneva, CH.
B PieskeCharité Universitätsmedizin Berlin, Department of Internal Medicine and Cardiology, Berlin, DE.
L ShapiraDepartment of Periodontology, Hebrew University - Hadassah Faculty of Dental Medicine, Jerusalem, IL.
M ShechterLeviev Heart Center, Chaim Sheba Medical Center, tel Hashomer and the Sackler Faculty of Medicine, Tel Aviv University, IL.
M TonettiDepartment of Periodontology, The University of Hong Kong, Prince Philip Dental Hospital, HK.
C VlachopoulosDepartment of Cardiology, National and Kapodistrian University of Athens, GR.
G WimmerDepartment of Prosthetic Dentistry, School of Dental Medicine, Karl-Franzens University Graz, AT.
National and Kapodistrian University of Athens · GRUniversity of Birmingham · GBAcademic Center for Dentistry Amsterdam · NLEastman Dental Hospital · GBGerman Centre for Cardiovascular Research · DEHadassah Academic College · ILHebrew University of Jerusalem · ILHôpital Rothschild · FRHospital Universitario Ramón y Cajal · ESInserm · FRInstituto Cajal · ESInstituto de Investigación Sanitaria de Santiago · ESLondon School of Hygiene & Tropical Medicine · GBTel Aviv University · ILUniversidad Complutense de Madrid · ESUniversity of Bonn · DEUniversity of Graz · ATUniversity of Hong Kong · HKUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In Europe cardiovascular disease (CVD) is responsible for 3.9 million deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to heart failure) the major cause of these CVD related deaths. Periodontitis is also a chronic non-communicable disease (NCD) with a high prevalence, being severe periodontitis, affecting 11.2% of the world's population, the sixth most common human disease. Material and Methods: There is now a significant body of evidence to support independent associations between severe periodontitis and several NCDs, in particular CVD. In 2012 a joint workshop was held between the European Federation of Periodontology (EFP) and the American Academy of Periodontology to review the literature relating periodontitis and systemic diseases, including CVD. In the last five years important new scientific information has emerged providing important emerging evidence to support these associations. Results and Conclusions: The present review reports the proceedings of the workshop jointly organised by the EFP and the World Heart Federation (WHF), which has updated the existing epidemiological evidence for significant associations between periodontitis and CVD, the mechanistic links and the impact of periodontal therapy on cardiovascular and surrogate outcomes. This review has also focused on the potential risk and complications of periodontal therapy in patients on anti thrombotic therapy and has made recommendations for dentists, physicians and for patients visiting both the dental and medical practices.

Indexed as

Cardiovascular DiseasesEuropeHumansIncidencePeriodontitisantitrombotic therapyatherosclerosisbacteremiacardiovascular diseaseschronic inflammationperiodontal therapyPeriodontitis

Identifiers

PMID32489774
PMCPMC7218770
OpenAlexW3008047705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.