ArticleClinical and translational allergy2020
Male sex is strongly associated with IgE-sensitization to airborne but not food allergens: results up to age 24 years from the BAMSE birth cohort.
Article in Clinical and translational allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation.Mutation research. Reviews in mutation researchPooled it
- Reported Symptoms Upon Exposure to Aeroallergen Highly Predict Allergen Sensitization Among 12-Year-Old Children.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Response rates and representativeness from birth to young adulthood in a Swedish birth cohort.International journal of epidemiology · 2026Article
- Tree pollen allergen sensitization: Prevalence, risk factors, and geographic variation in the United States.The journal of allergy and clinical immunology. Global · 2026Article
- Longitudinal protein profiling of blood during childhood into early adulthood.Nature communications · 2026Article
- Sublingual immunotherapy in children with asthma: A population-based register study.The journal of allergy and clinical immunology. Global · 2026Article
- Allergen-specific IgE sensitization spectrum in 4,166 children with allergic diseases at a county-level hospital in eastern China: a retrospective cross-sectional study.Frontiers in allergy · 2026Article
- Epidemiology and allergen sensitisation in patients undergoing prick testing.The World Allergy Organization journal · 2025Article
- Gender and Age-Related Trends in Inhalant Allergen Sensitization in Lithuania: A Cross-Sectional Study.International journal of molecular sciences · 2025Article
- Gender and Allergy: Mechanisms, Clinical Phenotypes, and Therapeutic Response-A Position Paper from the Società Italiana di Allergologia, Asma ed Immunologia Clinica (SIAAIC).International journal of molecular sciences · 2025Review
- Characteristics related to biomarkers of neutrophil, eosinophil, and mast cell activation.Scientific reports · 2025Article
- Article
- Distinct Phenotypes of Peripheral Innate Lymphoid Cells and T Cells in Type 2 and Non-Type 2 Asthma.Clinical and translational allergy · 2025Article
- Importance of allergic sensitisation for normal range of fractional exhaled nitric oxide in adolescents.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
- Article
- Snus and Cardiometabolic Health Markers Among Swedish Young Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Aeroallergen sensitization rate and its multifactorial influences in continental Croatia: a cross-sectional study.Croatian medical journal · 2025Article
- Biomarkers of dietary PUFA intake in childhood and adolescence in relation to cardiometabolic risk factors in young adulthood: a prospective cohort study in Sweden.The American journal of clinical nutrition · 2025Article
- How Families Manage the Home Environment for Young People With Asthma and Allergic Sensitisation: A Qualitative Study.Pediatric pulmonology · 2025Article
- Increasing prevalence of galactose-α-1,3-galactose sensitization in the Danish general adult population.Allergy · 2025Article
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Authors and funding
12 authors.
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Abstract
backgroundUp to half of the population in high-income countries has allergen-specific IgE antibodies. However, data regarding sex differences of IgE-sensitization from childhood to adulthood is limited.
objectiveTo explore IgE-sensitization to common foods and airborne allergens in relation to sex over time in a population-based cohort followed up to young adulthood.
methodsThe Swedish population-based birth cohort BAMSE includes 4089 subjects who have been followed regularly with questionnaires and clinical investigations. A recent 24-year follow-up included 3069 participants (75%). Sera collected at 4, 8, 16 and 24 years were analyzed for IgE-antibodies to 14 common foods and airborne allergens.
resultsAt 24 years sensitization to foods had decreased compared to previous follow-ups affecting 8.4%, while sensitization to airborne allergens was more common, affecting 42.2%. Male sex was associated with IgE-sensitization to airborne allergens at all ages (overall OR: 1.68, 95% CI 1.46-1.94) while there was no statistically significant association between sex and sensitization to food allergens (overall OR: 1.10, 95% CI 0.93-1.32). Levels of allergen-specific IgE did not differ significantly between males and females for any of the tested foods or airborne allergens at any age, following adjustment for multiple comparisons.
conclusionIgE-sensitization to airborne allergens increases with age up to young adulthood, whereas sensitization to food allergens seems to level off. Male sex is strongly associated with IgE-sensitization to airborne allergens from early childhood up to young adulthood. In contrast, there is little evidence for associations between sex and IgE-sensitization to foods.
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