ArticleIranian journal of basic medical sciences2020
Analysis of the active fraction of Iranian
Article in Iranian journal of basic medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Green synthesis of PEGylated iron oxide nanoparticles of Eriobotrya japonica leaves extract in combination with B3, against Plasmodium falciparum 3D7 strain.Tropical medicine and health · 2025Article
- Antimalarial Effects of Nano Chloroquine Loaded Curcumin In vivo.Infectious disorders drug targets · 2024Article
- Toxins from Animal Venoms as a Potential Source of Antimalarials: A Comprehensive Review.Toxins · 2023Review
- Antiprotozoal Effect of Snake Venoms and Their Fractions: A Systematic Review.Pathogens (Basel, Switzerland) · 2021Review
- The Metabolomic Profiles of Sera of Mice Infected with Plasmodium berghei and Treated by Effective Fraction of Naja naja oxiana UsingActa parasitologica · 2021Article
- Antimalarial effects of the hydroalcoholic extract ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- In Vitro Antimalarial Activity of Chloroquine-Crocus Sativus Conjugated to Chitosan Nanocomposits against 3D7 and K1 Strains ofIranian journal of parasitologyArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMalaria is an important parasitic disease with high morbidity and mortality in tropical areas. Resistance to most antimalarial drugs has encouraged the development of new drugs including natural products. Venom is a complex mixture of active pharmaceutical ingredients. The purpose of this study was to investigate the antimalarial activity of purified fractions of MATERIALS AND
methodsLyophilized venom was purified with a Sephacryl S-200 HR column and the fractions lyophilized and inhibitory concentration 50% against
resultsThe active fraction from the ion exchange column had a 50% inhibitory concentration of 0.026 µg/ml on
conclusionThe metabolites were succinic acid, l-glutamic acid, pyruvic acid, cholesterol, and NAD. The changes in the Krebs cycle and metabolism pathways of nicotinamide and pyruvate were noticeable.
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Registered trials
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