Evidence map›Paper›PMID 32489292›Full record

ArticleSaudi journal of biological sciences2020

Curcumin-loaded cockle shell-derived calcium carbonate nanoparticles: A novel strategy for the treatment of lead-induced hepato-renal toxicity in rats.

Maryam Muhammad Mailafiya, Kabeer Abubakar, Samaila Musa Chiroma, Abubakar Danmaigoro, Ezamin Bin Abdul Rahim, Mohamad Aris Mohd Moklas, Zuki Abu Bakar Zakaria

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Plant Polyphenols: Potential Antidotes for Lead Exposure.Biological trace element research · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Maryam Muhammad MailafiyaDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.
Kabeer AbubakarDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.
Samaila Musa ChiromaDepartment of Human Anatomy, Faculty of Basic Medical Sciences, University of Maiduguri, 600230 Maiduguri, Borno State, Nigeria.
Abubakar DanmaigoroDepartment of Veterinary Anatomy, Faculty of Veterinary Medicine, Usman Danfodiyo University, 840213, Sultan Abubakar, Sokoto State, Nigeria.
Ezamin Bin Abdul RahimDepartment of Radiology, Faculty of Medicine and Health Sciences, University Putra Malaysia, Serdang 43400, Selangor Darul Ehsan, Malaysia.
Mohamad Aris Mohd MoklasDepartment of Human Anatomy, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia.
Zuki Abu Bakar ZakariaDepartment of Preclinical Sciences Faculty of Veterinary Medicine, University Putra Malaysia, Serdang 43400, Selangor Darul Ehsan, Malaysia.
Universiti Putra Malaysia · MYUniversity of Maiduguri · NGUsmanu Danfodiyo University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lead (Pb) toxicity affects the hepatic and renal systems resulting to homeostasis imbalance. Curcumin is a strong antioxidant but has restrained clinical applications due to its poor bioavailability. Nanomedicine showed promising potentials in drug delivery and has brought forth the use of cockle shell-derived aragonite calcium carbonate nanoparticles (CSCaCO

Indexed as

Cockle shellCurcuminHepato-renal injuriesLead-toxicityNanoparticlesOral therapeutics

Identifiers

PMID32489292
PMCPMC7253904
OpenAlexW3011436042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.