Evidence map›Paper›PMID 32489130›Full record

ArticleDrug delivery2020

Preparation of hydroxy genkwanin nanosuspensions and their enhanced antitumor efficacy against breast cancer.

Hui Ao, Yijing Li, Haowen Li, Yian Wang, Meihua Han, Yifei Guo, Rongxing Shi, Feng Yue, Xiangtao Wang

Abstract read
In one paragraph

Article in Drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Total Flavonoids inInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Research progress on the preparation and application of flavonoid nanocrystals.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hui AoInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.
Yijing Li
Haowen LiInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.
Yian WangInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.
Meihua HanInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.
Yifei GuoInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.
Rongxing ShiChina-Japan Friendship Hospital, Bejing, China.
Feng YueGuangdong Jiabo Pharmaceutical Co., Ltd., Guangdong, People's Republic of China.
Xiangtao WangInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxy genkwanin (HGK), a flavonoid compound from natural resources, showed good inhibition against the growth of breast tumor cells. However, the poor solubility restricted the further study and the

Indexed as

Drug Delivery SystemsAnimalsAntineoplastic Agents, PhytogenicBreast NeoplasmsDrug LiberationFlavonesFlavonoidsHumansMCF-7 CellsMiceNanocompositesSolubilitySuspensionsTreatment OutcomeXenograft Model Antitumor AssaysAntineoplastic Agents, PhytogenicFlavonesFlavonoidsgenkwaninSuspensionsantitumor efficacybreast cancercytotoxicityHydroxy genkwaninnanosuspensions

Identifiers

PMID32489130
PMCPMC8216440

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.