Evidence map›Paper›PMID 32488959›Full record

ArticleClinical and experimental dental research2020

Trends and clinicopathological characteristics of oral squamous cell carcinomas reported at a tertiary cancer hospital in Nepal during 1999 to 2009.

Rashmi Gajurel, Dej Kumar Gautam, Chin Bahadur Pun, Hari Prasad Dhakal, Beáta Éva Petrovski, Daniela Elena Costea, Dipak Sapkota

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Article in Clinical and experimental dental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  8. Mouth Self-Examination for Prevention and Control of Oral Cavity Cancer.JNMA; journal of the Nepal Medical Association · 2020
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  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Rashmi GajurelCentre for International Health, University of Bergen, Bergen, Norway.
Dej Kumar GautamDepartment of Surgical Oncology, B.P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal.
Chin Bahadur PunDepartment of Pathology, B. P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal.
Hari Prasad DhakalDepartment of Pathology and Laboratory Medicine, Nepal Cancer Hospital and Research Centre, Lalitpur, Nepal.
Beáta Éva PetrovskiDepartment of Faculty Administration, IT-section, Faculty of Dentistry, University of Oslo, Oslo, Norway.
Daniela Elena CosteaGade Laboratory for Pathology and Center for Cancer Biomarkers CCBio, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Dipak SapkotaDepartment of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway.ORCID 0000-0003-0061-825X
University of Oslo · NOB.P. Koirala Memorial Cancer Hospital · NPHaukeland University Hospital · NONepal Cancer Hospital and Research Center · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveReliable data describing the trends and clinicopathological characteristics of oral squamous cell carcinoma (OSCC) in the Nepalese population are very limited. The current study aimed to examine the demographics, trend, and clinicopathological characteristics of OSCC reported to the main referral/tertiary cancer hospital, the B.P. Koirala Memorial Cancer Hospital (BPKMCH) in Nepal for a period of 11 years (1999-2009). MATERIAL AND

methodsThis is a cross-sectional study. Data were retrieved retrospectively from hospital register maintained in the Department of Ear, Nose, Throat at BPKMCH, categorized into demographic and clinicopathological variables and SPSS (V25) was used for the analysis.

resultsIn a period of 11 years, 3,452 cases of head and neck cancer were registered at the Department of Ear, Nose, Throat, BPKMCH. Out of 1,111 oral cancer cases, 1,081 (97.3%) were OSCC. A trend for increasing number of OSCCs presenting to BPKMCH was observed during that period. OSCC was found to be more common among males (73.0%), Brahmin/Chhetri ethnic groups (33.0%), in age group of 51-60 years (31.9%), and in Terai region (62.0%). Tongue (42.8%) was the most common site, followed by buccal mucosa (27.2%). Nevertheless, when stratified with respect to the geographical location and ethnicity, buccal mucosa was the most common site for OSCC in Terai region (63.9%, p = .002) and in Madhesi ethnic group (34.2%, p < .001). Majority of OSCC cases were diagnosed at advanced stage (49.7%, Stage IV) and received a combination therapy (42.0%).

conclusionsHospital-based records can provide valuable information on disease characteristics in countries like Nepal. This study revealed that the clinicopathological characteristics of OSCC in Nepal follow the global trend. Nevertheless, relationship between specific intraoral sites for OSCC with geographic location and ethnic groups is an interesting observation and requires further population-based studies to clarify these findings.

Indexed as

AdultCancer Care FacilitiesCarcinoma, Squamous CellCross-Sectional StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedMouth NeoplasmsNepalPrognosisRetrospective StudiesRisk FactorsTertiary Care CentersTime FactorsepidemiologyNepaloral canceroral squamous cell carcinoma

Identifiers

PMID32488959
PMCPMC7301398
OpenAlexW2998977402

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.