ArticleJournal of the American Geriatrics Society2020
The Effect of Personality Traits on Risk of Incident Pre-dementia Syndromes.
Article in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Association of motoric cognitive risk syndrome with depression in older adults: a meta-analysis and systematic review of cross-sectional and cohort studies.BMC geriatrics · 2024Pooled it
- Inhibition of return mediates the relationship between openness to experience and visuospatial ability.PeerJ · 2026Article
- Patterns and predictors of cognitive function and post-traumatic growth in cancer patients: a latent profile analysis.Frontiers in psychiatry · 2026Article
- Adverse childhood experiences and their differential relationships with transdiagnostic mental health outcomes in young adults.Psychological medicine · 2025Article
- Marital Status-Specific Associations Between Multidomain Leisure Activities and Cognitive Reserve in Clinically Unimpaired Older Adults: Based on a National Chinese Cohort.Brain sciences · 2025Article
- Association between personality profiles and motoric cognitive risk syndrome in community-dwelling older adults: a person-centered approach.BMC psychiatry · 2025Article
- Association between positive control in self-perceptions of aging and motoric cognitive risk syndrome among Chinese community-dwelling older adults: a cross-sectional study.BMC geriatrics · 2023Article
- Association Between Neuroticism and Dementia on Healthcare Use: A Multi-Level Analysis Across 27 Countries from The Survey of Health, Ageing and Retirement in Europe (SHARE).Journal of Alzheimer's disease : JAD · 2023Article
- Facets of conscientiousness and motoric cognitive risk syndrome.Journal of psychiatric research · 2022Article
- Examining Association of Personality Characteristics and Neuropsychiatric Symptoms in Post-COVID Syndrome.Brain sciences · 2022Article
- Increased Social Support Reduces the Incidence of Motoric Cognitive Risk Syndrome.Innovation in aging · 2022Article
- Association of Type D personality and mild cognitive impairment in patients with hypertension.Frontiers in psychology · 2022Article
- Purpose in Life and Motoric Cognitive Risk Syndrome: Replicable Evidence from Two National Samples.Journal of the American Geriatrics Society · 2021Article
- Motoric Cognitive Risk Syndrome: Symptoms, Pathology, Diagnosis, and Recovery.Frontiers in aging neuroscience · 2021Review
- Hazardous alcohol consumption among older adults: A comprehensive and multi-national analysis of predictive factors in 13,351 individuals.European psychiatry : the journal of the Association of European Psychiatrists · 2020Article
- The relationship between personality traits and Alzheimer's disease: a narrative review.Frontiers in neurologyReview
- Do Personality Traits Influence the Association Between Depression and Dementia in Old Age?Gerontology & geriatric medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectivesPersonality traits have been shown to be associated with the risk of dementia; less is known about their association with pre-dementia syndromes. The aim of the present study was to examine the role of personality traits as predictors of incident pre-dementia, motoric cognitive risk (MCR), and mild cognitive impairment (MCI) syndromes.
designWe prospectively examined the association between five personality traits (neuroticism, extraversion, conscientiousness, agreeableness, and openness) and the risk of incident MCR or MCI. MCR builds on MCI operational definitions, substituting the cognitive impairment criterion with slow gait, and it is associated with increased risk for both Alzheimer's disease and vascular dementia.
settingCommunity based.
participantsNondemented participants (n = 524; 62% women) aged 65 years and older. MEASUREMENTS: Cox proportional hazard analysis, adjusted for demographics and disease burden, was used to evaluate the risk of each pre-dementia syndrome based on baseline personality traits, measured using the Big Five Inventory.
resultsOver a median follow-up of 3 years, 38 participants developed incident MCR, and 69 developed incident MCI (41 non-amnestic and 28 amnestic subtypes). Openness was associated with a reduced risk of developing incident MCR (adjusted hazard ratio [aHR] = .94; 95% confidence interval [CI] = .89-.99), whereas neuroticism was associated with an increased risk of incident non-amnestic MCI (aHR = 1.06; 95% CI = 1.01-1.11). These associations remained significant even after considering the confounding effects of lifestyle or mood. None of the personality traits were associated with MCI overall or amnestic MCI.
conclusionThese findings provide evidence of a distinct relationship between personality traits and development of specific pre-dementia syndromes. J Am Geriatr Soc 68:1554-1559, 2020.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.