Evidence map›Paper›PMID 32488847›Full record

ArticleJournal of molecular neuroscience : MN2020

Electro-Acupuncture Inhibits p66Shc-Mediated Oxidative Stress to Facilitate Functional Recovery After Spinal Cord Injury.

Ming Cheng, Xiaojing Wu, Fei Wang, Bo Tan, Jiang Hu

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ming ChengDepartment of Orthopedics, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, Chengdu, 610072, China.
Xiaojing WuDepartment of Orthopedics, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, Chengdu, 610072, China.
Fei WangDepartment of Orthopedics, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, Chengdu, 610072, China.
Bo TanDepartment of Orthopedics, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, Chengdu, 610072, China.
Jiang HuDepartment of Orthopedics, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, Chengdu, 610072, China. hujiangbiology@163.com.ORCID http://orcid.org/0000-0003-3858-7524
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital · CNThird People's Hospital of Chengdu · CN

Funding

the Youth Innovation Project of Sichuan Medical Association [Grant No. Q17073]
6 · The paper itself

Abstract

Oxidative stress is the core problem in improving secondary spinal cord injury (SCI). To investigate the effect of electro-acupuncture with different frequencies on neuroinflammation, oxidative stress injury, as well as related signaling pathways, male Sprague-Dawley (SD) rats were induced using operation for model SCI and then treated with electrical stimulation at low frequency (2 mA, 0.2 Hz), medium frequency (2 mA, 50 Hz), and high frequency (2 mA, 100 Hz), respectively. Here, we first demonstrated that the JNK/p66

Indexed as

Oxidative StressAnimalsApoptosisElectroacupunctureMaleMAP Kinase Kinase 4Neuronsp38 Mitogen-Activated Protein KinasesRatsRats, Sprague-DawleySpinal Cord InjuriesSrc Homology 2 Domain-Containing, Transforming Protein 1MAP Kinase Kinase 4p38 Mitogen-Activated Protein KinasesShc1 protein, ratSrc Homology 2 Domain-Containing, Transforming Protein 1Electro-acupunctureJNK/p66ShcOxidative stressROSSpinal cord injury

Identifiers

PMID32488847
OpenAlexW3031219067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.