Evidence map›Paper›PMID 32488818›Full record

ArticleDigestive diseases and sciences2021

FDG-PET-CT Enterography Helps Determine Clinical Significance of Suspected Ileocecal Thickening: A Prospective Study.

Abhi K Singh, Rajender Kumar, Pankaj Gupta, Praveen Kumar-M, Shubhra Mishra, Harshal S Mandavdhare, Harjeet Singh, Kaushal K Prasad, Usha Dutta, Vishal Sharma

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Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Evidence-based approach to diagnosis and management of abdominal tuberculosis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
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4 · The record

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5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Abhi K SinghDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Rajender KumarDepartment of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Pankaj GuptaDepartment of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Praveen Kumar-MDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Shubhra MishraDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Harshal S MandavdhareDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Harjeet SinghDepartment of General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Kaushal K PrasadDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Usha DuttaDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Vishal SharmaDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. docvishalsharma@gmail.com.ORCID 0000-0003-2472-3409
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIleocecal thickening (ICT) on imaging could result from diverse etiologies but may also be clinically insignificant.

aimEvaluation of role of combined 2-deoxy-2-fluorine-18-fluoro-D-glucose(

methodsThis prospective study enrolled consecutive patients with suspected ICT on ultrasound. Patients were evaluated with PET-CTE and colonoscopy. The patients were divided into: Group A (clinically significant diagnosis) or Group B (clinically insignificant diagnosis) and compared for various clinical and radiological findings. The two groups were compared for maximum standardized uptake values of terminal ileum, ileo-cecal valve, cecum and overall.

resultsOf 34 patients included (23 males, mean age: 40.44 ± 15.40 years), 12 (35.3%) had intestinal tuberculosis, 11 (32.4%) Crohn's disease, 3 (8.8%) other infections, 1 (2.9%) malignancy, 4 (11.8%) non-specific terminal ileitis while 3 (8.8%) had normal colonoscopy and histology. The maximum standardized uptake value of the ileocecal area overall (SUVmax-ICT-overall) was significantly higher in Group A (7.16 ± 4.38) when compared to Group B (3.62 ± 9.50, P = 0.003). A cut-off of 4.50 for SUVmax-ICT-overall had a sensitivity of 70.37% and a specificity of 100% for prediction of clinically significant diagnosis. Using decision tree model, the SUVmax-ICT with a cut-off of 4.75 was considered appropriate for initial decision followed by the presence of mural thickening in the next node.

conclusionPET-CTE can help in discrimination of clinically significant and insignificant diagnosis. It may help guide the need for colonoscopy in patients suspected to have ICT on CT.

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyRadiopharmaceuticalsAdultBiopsyClinical Decision-MakingColonoscopyCrohn DiseaseDecision TreesFemaleHumansIleitisIleocecal ValveIntestinal NeoplasmsMaleMiddle AgedFluorodeoxyglucose F18RadiopharmaceuticalsCrohn diseaseGastrointestinal tuberculosisIleocecal valveInflammatory bowel diseaseTuberculous peritonitis

Identifiers

PMID32488818
OpenAlexW3030691397

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.